DCXR and GLRX2

Data Source:
BioGRID (two hybrid)

		DCXR	GLRX2
Description		dicarbonyl and L-xylulose reductase	glutaredoxin 2
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GO Annotations	Cellular Component	Nucleus Cytoplasmic Microtubule Plasma Membrane Microvillus Brush Border Extracellular Exosome	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Dendrite Neuronal Cell Body Intracellular Membrane-bounded Organelle
	Molecular Function	Carbonyl Reductase (NADPH) Activity Protein Binding Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor Identical Protein Binding L-xylulose Reductase (NAD+) Activity L-xylulose Reductase (NADP+) Activity	Protein Disulfide Isomerase Activity Protein Binding Arsenate Reductase (glutaredoxin) Activity Electron Transfer Activity Protein Disulfide Oxidoreductase Activity Glutathione Disulfide Oxidoreductase Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding
	Biological Process	Xylulose Metabolic Process Glucose Metabolic Process NADP Metabolic Process Glucuronate Catabolic Process To Xylulose 5-phosphate D-xylose Metabolic Process	Regulation Of Transcription, DNA-templated Glutathione Metabolic Process Apoptotic Process Aging Response To Temperature Stimulus Regulation Of Signal Transduction Response To Organic Substance Protein Phosphopantetheinylation Electron Transport Chain Cell Differentiation DNA Protection Response To Hydrogen Peroxide Cell Redox Homeostasis Response To Redox State Cellular Response To Superoxide
Pathways		Formation of xylulose-5-phosphate Essential pentosuria
Drugs		Dihydrogenphosphate Nicotinamide adenine dinucleotide phosphate	Glutathione
Diseases		Pentosuria
GWAS		Refractive error ( 32231278)	Blood protein levels ( 29875488)
Interacting Genes		3 interacting genes: APP CRADD GLRX2	4 interacting genes: DCXR ELF5 FBXO7 TXNRD1
Entrez ID		51181	51022
HPRD ID		16320	12112
Ensembl ID		ENSG00000169738	ENSG00000023572
Uniprot IDs		A0A384NY14 Q7Z4W1	Q9NS18
PDB IDs		1PR9 1WNT 3D3W	2CQ9 2FLS 2HT9
Enriched GO Terms of Interacting Partners?
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