PHF20L1 and WWP1

Data Source:
BioGRID (two hybrid)

		PHF20L1	WWP1
Description		PHD finger protein 20 like 1	WW domain containing E3 ubiquitin protein ligase 1
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GO Annotations	Cellular Component	NSL Complex	Ubiquitin Ligase Complex Nucleus Cytoplasm Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Histone Acetylation	Protein Polyubiquitination Signal Transduction Central Nervous System Development Protein Ubiquitination Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell
Pathways			Downregulation of ERBB4 signaling Stimuli-sensing channels Regulation of RUNX2 expression and activity Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Body fat percentage ( 31752434) Mean reticulocyte volume ( 32888494) Metabolite levels ( 23823483) Thyroid stimulating hormone levels ( 32769997)	Estimated glomerular filtration rate ( 31152163)
Interacting Genes		10 interacting genes: APP CASP10 ELAVL4 KDM1A LRRK2 LYAR TERT UBC WWP1 ZNF471	55 interacting genes: ARRDC1 ARRDC2 ARRDC3 ASH2L ATN1 CLCN5 CPSF6 DAG1 DAZAP2 DIDO1 EWSR1 FAM189A2 FBXL18 HSPB1 IKBKG IL2RG IL6R KLF2 KLF5 LAPTM5 LATS1 LNX1 LZTR1 MACROH2A2 MIR19A MIR19B1 NFE2 NOTCH1 PCBD1 PHF20L1 PRKAA2 PYGM RASA1 RNF11 RTN4 RUNX1 SCNN1A SFTPC SMAD3 SMAD5 STAT6 TFAP2A TGIF1 TP53BP2 TRAF4 UBC UBE2D1 UBE2D2 UBE2D3 UBE2L3 WASL WBP1 WBP2 YWHAQ ZNF638
Entrez ID		51105	11059
HPRD ID		15125	03811
Ensembl ID		ENSG00000129292	ENSG00000123124
Uniprot IDs		A0A0A0MQS0 A0A0A8K9A6 A8MW92 Q9H8G4	Q9H0M0
PDB IDs		2EQM 2EQU 2JTF 6L0X 6L10 6L1C 6L1F 6L1I 6L1P	1ND7 2OP7 5HPS 5HPT 6J1X 6J1Y
Enriched GO Terms of Interacting Partners?
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