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F11R and PEX19
Data Source:
BioGRID
(two hybrid)
F11R
PEX19
Description
F11 receptor
peroxisomal biogenesis factor 19
Image
GO Annotations
Cellular Component
Plasma Membrane
Cell-cell Junction
Bicellular Tight Junction
Integral Component Of Membrane
Cell Junction
Cytoplasmic Vesicle
Protein-containing Complex
Slit Diaphragm
Extracellular Exosome
Tight Junction
Nucleoplasm
Cytoplasm
Peroxisome
Peroxisomal Membrane
Cytosol
Brush Border Membrane
Protein-containing Complex
Molecular Function
Virus Receptor Activity
Integrin Binding
Protein Binding
PDZ Domain Binding
Protein Homodimerization Activity
Cadherin Binding
Protein Binding
Peroxisome Membrane Targeting Sequence Binding
Peroxisome Membrane Class-1 Targeting Sequence Binding
Protein N-terminus Binding
ATPase Binding
Biological Process
Regulation Of Cytokine Production
Inflammatory Response
Leukocyte Cell-cell Adhesion
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cell Shape
Response To Radiation
Extracellular Matrix Organization
Actomyosin Structure Organization
Regulation Of Actin Cytoskeleton Organization
Negative Regulation Of GTPase Activity
Positive Regulation Of Rho Protein Signal Transduction
Maintenance Of Blood-brain Barrier
Memory T Cell Extravasation
Positive Regulation Of GTPase Activity
Positive Regulation Of Blood Pressure
Viral Entry Into Host Cell
Intestinal Absorption
Leukocyte Migration
Regulation Of Cytoskeleton Organization
Negative Regulation Of Stress Fiber Assembly
Bicellular Tight Junction Assembly
Cellular Response To Mechanical Stimulus
Protein Localization To Plasma Membrane
Establishment Of Endothelial Intestinal Barrier
Regulation Of Membrane Permeability
Cell-cell Adhesion
Positive Regulation Of Platelet Aggregation
Protein Localization To Bicellular Tight Junction
Positive Regulation Of Establishment Of Endothelial Barrier
Regulation Of Actin Cytoskeleton Reorganization
Regulation Of Bicellular Tight Junction Assembly
Protein Targeting To Peroxisome
Peroxisome Organization
Peroxisome Fission
Protein Import Into Peroxisome Membrane
Protein Stabilization
Transmembrane Transport
Chaperone-mediated Protein Folding
Chaperone-mediated Protein Transport
Establishment Of Protein Localization To Peroxisome
Negative Regulation Of Lipid Binding
Pathways
Cell surface interactions at the vascular wall
Integrin cell surface interactions
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
Tight junction interactions
ABC transporters in lipid homeostasis
Class I peroxisomal membrane protein import
Class I peroxisomal membrane protein import
Drugs
Diseases
Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS
Inflammatory bowel disease (
23128233
)
Night sleep phenotypes (
27126917
)
Interacting Genes
30 interacting genes:
AFDN
ASIP
BDNF
CAMLG
CASK
CGN
CSNK2A1
F2RL2
ITGAL
JAGN1
MARCHF2
MMP14
MPDZ
MYADM
PARD3
PEX19
PGAP2
PICK1
PRKCA
PTPRB
RABAC1
SGTA
SLC30A2
SLC35A1
SNAP47
STRIT1
TJP1
TMEM100
TMEM147
TMEM86B
38 interacting genes:
ABCD1
ABCD2
ABCD3
BCL2L11
CDC25A
CDKN2A
EIF1B
F11R
FKBP7
GSKIP
IFNB1
IL23A
IRF3
KIFAP3
MFSD5
NAT8L
OIP5
PEX10
PEX11A
PEX11B
PEX12
PEX13
PEX14
PEX16
PEX26
PEX3
PMP22
PPIB
PSORS1C2
PXMP4
SLC25A17
SLC34A1
SMAD2
SRPK1
STK3
SUOX
TMEM54
TXN2
Entrez ID
50848
5824
HPRD ID
12038
02610
Ensembl ID
ENSG00000158769
ENSG00000162735
Uniprot IDs
Q6FIB4
Q9Y624
A0A0S2Z497
P40855
PDB IDs
1NBQ
3EOY
3TSZ
4ODB
2W85
2WL8
3AJB
3MK4
5LNF
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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