PEX19 and EIF1B

Data Source:
BioGRID (two hybrid)

		PEX19	EIF1B
Description		peroxisomal biogenesis factor 19	eukaryotic translation initiation factor 1B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Brush Border Membrane Protein-containing Complex	Cellular_component Eukaryotic 43S Preinitiation Complex
	Molecular Function	Protein Binding Peroxisome Membrane Targeting Sequence Binding Peroxisome Membrane Class-1 Targeting Sequence Binding Protein N-terminus Binding ATPase Binding	RNA Binding Translation Initiation Factor Activity Protein Binding Ribosomal Small Subunit Binding
	Biological Process	Protein Targeting To Peroxisome Peroxisome Organization Peroxisome Fission Protein Import Into Peroxisome Membrane Protein Stabilization Transmembrane Transport Chaperone-mediated Protein Folding Chaperone-mediated Protein Transport Establishment Of Protein Localization To Peroxisome Negative Regulation Of Lipid Binding	Translational Initiation Regulation Of Translational Initiation
Pathways		ABC transporters in lipid homeostasis Class I peroxisomal membrane protein import Class I peroxisomal membrane protein import
Drugs
Diseases		Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS			Refractive error ( 32231278)
Interacting Genes		38 interacting genes: ABCD1 ABCD2 ABCD3 BCL2L11 CDC25A CDKN2A EIF1B F11R FKBP7 GSKIP IFNB1 IL23A IRF3 KIFAP3 MFSD5 NAT8L OIP5 PEX10 PEX11A PEX11B PEX12 PEX13 PEX14 PEX16 PEX26 PEX3 PMP22 PPIB PSORS1C2 PXMP4 SLC25A17 SLC34A1 SMAD2 SRPK1 STK3 SUOX TMEM54 TXN2	6 interacting genes: ATXN1 DVL2 DVL3 PEX19 SPG21 TRIM38
Entrez ID		5824	10289
HPRD ID		02610	17032
Ensembl ID		ENSG00000162735	ENSG00000114784
Uniprot IDs		A0A0S2Z497 P40855	O60739 Q6FG85
PDB IDs		2W85 2WL8 3AJB 3MK4 5LNF
Enriched GO Terms of Interacting Partners?
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