PAH and RPS24

Data Source:
BioGRID (two hybrid)

		PAH	RPS24
Description		phenylalanine hydroxylase	ribosomal protein S24
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GO Annotations	Cellular Component	Cytosol	Nucleus Nucleoplasm Endoplasmic Reticulum Cytosol Small Ribosomal Subunit Membrane Cytosolic Small Ribosomal Subunit
	Molecular Function	Phenylalanine 4-monooxygenase Activity Iron Ion Binding	RNA Binding Structural Constituent Of Ribosome Translation Initiation Factor Binding
	Biological Process	L-phenylalanine Catabolic Process Tyrosine Biosynthetic Process Cellular Amino Acid Biosynthetic Process Neurotransmitter Biosynthetic Process Catecholamine Biosynthetic Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription Erythrocyte Homeostasis Ribosomal Small Subunit Biogenesis
Pathways		Phenylketonuria Phenylalanine metabolism	L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs		Phenylalanine Sapropterin Norepinephrine Quinonoid 7,8-Tetrahydrobiopterin beta-2-Thienyl-L-alanine L-erythro-7,8-dihydrobiopterin D-norleucine Droxidopa
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient	Diamond-Blackfan anemia (DBA)
GWAS		Amino acid levels ( 26068415) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood metabolite levels ( 24816252) Metabolite levels (small molecules and protein measures) ( 27005778) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)	California verbal learning test score ( 31596458) Diverticular disease ( 30177863) Metabolite levels ( 23823483)
Interacting Genes		3 interacting genes: PCBD1 QDPR RPS24	7 interacting genes: DUX4 ERCC6 PAH PCBD1 PNISR STK17B TAF9
Entrez ID		5053	6229
HPRD ID		08943	03877
Ensembl ID		ENSG00000171759	ENSG00000138326
Uniprot IDs		A0A024RBG4 P00439	A0A2R8Y849 P62847
PDB IDs		1DMW 1J8T 1J8U 1KW0 1LRM 1MMK 1MMT 1PAH 1TDW 1TG2 2PAH 3PAH 4ANP 4PAH 5FII 5PAH 6HPO 6HYC 6N1K 6PAH	4UG0 4V6X 5A2Q 5AJ0 5FLX 5LKS 5OA3 5T2C 5VYC 6EK0 6FEC 6G18 6G4S 6G4W 6G51 6G53 6G5H 6G5I 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP 6XA1 6Y0G 6Y2L 6Y57 6YBW 6Z6L 6Z6M 6Z6N 6ZLW 6ZM7 6ZME 6ZMI 6ZMO 6ZMT 6ZMW 6ZN5 6ZOJ 6ZOK 6ZON 6ZP4 6ZVH 7K5I
Enriched GO Terms of Interacting Partners?
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