PAH

Description		phenylalanine hydroxylase
Image
GO Annotations	Cellular Component	Cytosol
	Molecular Function	Phenylalanine 4-monooxygenase Activity Iron Ion Binding
	Biological Process	L-phenylalanine Catabolic Process Tyrosine Biosynthetic Process Cellular Amino Acid Biosynthetic Process Neurotransmitter Biosynthetic Process Catecholamine Biosynthetic Process
Pathways		Phenylketonuria Phenylalanine metabolism
Drugs		Phenylalanine Sapropterin Norepinephrine Quinonoid 7,8-Tetrahydrobiopterin beta-2-Thienyl-L-alanine L-erythro-7,8-dihydrobiopterin D-norleucine Droxidopa
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Amino acid levels ( 26068415) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood metabolite levels ( 24816252) Metabolite levels (small molecules and protein measures) ( 27005778) Plasma free amino acid levels ( 30659259) Plasma free amino acid levels (adjusted for one other PFAA) ( 30659259) Plasma free amino acid levels (adjusted for twenty other PFAAs) ( 30659259) Serum metabolite levels ( 31636271) Serum metabolite levels (CMS) ( 31636271)
Novel Interacting Genes		1 novel interacting genes: APAF1
Interacting Genes		3 interacting genes: PCBD1 QDPR RPS24
Entrez ID		5053
HPRD ID		08943
Ensembl ID		ENSG00000171759
Uniprot IDs		A0A024RBG4 P00439
PDB IDs		1DMW 1J8T 1J8U 1KW0 1LRM 1MMK 1MMT 1PAH 1TDW 1TG2 2PAH 3PAH 4ANP 4PAH 5FII 5PAH 6HPO 6HYC 6N1K 6PAH
Enriched GO Terms of Interacting Partners?
Tagcloud ?