PAEP and HIBADH

Data Source:
BioGRID (two hybrid)

		PAEP	HIBADH
Description		progestagen associated endometrial protein	3-hydroxyisobutyrate dehydrogenase
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Small Molecule Binding	Protein Binding 3-hydroxyisobutyrate Dehydrogenase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor NADP Binding NAD Binding
	Biological Process	Apoptotic Process Multicellular Organism Development Positive Regulation Of Granulocyte Macrophage Colony-stimulating Factor Production Negative Regulation Of Sperm Capacitation Regulation Of Binding Of Sperm To Zona Pellucida	Valine Catabolic Process Branched-chain Amino Acid Catabolic Process
Pathways			Branched-chain amino acid catabolism
Drugs		12-Bromododecanoic Acid Palmitic Acid Glycerin	NADH
Diseases
GWAS			Alcohol consumption (drinks per week) ( 30643258) Asthma ( 31959851) Diastolic blood pressure ( 27841878) General risk tolerance (MTAG) ( 30643258) Kidney stones ( 31729369) Lead levels in blood ( 25820613) Pulse pressure ( 27841878) Response to fenofibrate (HDL cholesterol levels) ( 27002377) Systolic blood pressure ( 27841878)
Interacting Genes		22 interacting genes: A2M APP AQP6 AQP9 ARL13B COPS6 EEF1A1 ERVFRD-1 GORAB GPR42 GPX8 GRAMD2B HIBADH IFNLR1 IGSF21 LRIF1 PCDHGA4 PTPRC SMAD3 TMX2 UBE2E1 XRCC6	39 interacting genes: ADAM33 AGTRAP AIG1 AMELY AQP3 ASGR1 BRCA1 C2CD2L CDS2 CLEC2A CMTM7 CNIH2 COMT CTSA EFNA5 ERMP1 GOSR2 MAL NDUFB11 PAEP PLN PRAF2 PTCH1 RTP2 SCARB2 SEC22B SFT2D2 SNORC TFRC TM6SF2 TMEM14B TMEM222 TMEM60 TMEM86B TRIM63 UBIAD1 VAMP2 VAMP5 ZFPL1
Entrez ID		5047	11112
HPRD ID		01411	12238
Ensembl ID		ENSG00000122133	ENSG00000106049
Uniprot IDs		A0A024R8D8 A6XNE0 B2R4F9 B4E3C0 P09466	A0A024RA75 P31937
PDB IDs		4R0B	2GF2 2I9P
Enriched GO Terms of Interacting Partners?
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