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TLCD4 and CLCN7
Data Source:
BioGRID
(two hybrid)
TLCD4
CLCN7
Description
TLC domain containing 4
chloride voltage-gated channel 7
Image
No pdb structure
GO Annotations
Cellular Component
Cellular_component
Endoplasmic Reticulum
Integral Component Of Membrane
Nucleoplasm
Lysosomal Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Molecular Function
Molecular_function
Protein Binding
Voltage-gated Chloride Channel Activity
Chloride Channel Activity
Protein Binding
ATP Binding
Chloride Transmembrane Transporter Activity
Antiporter Activity
Biological Process
Biological_process
Lipid Homeostasis
Ion Transmembrane Transport
Chloride Transmembrane Transport
Pathways
Stimuli-sensing channels
Drugs
Diseases
Osteopetrosis, including: Osteopetrosis, severe neonatal or infantile forms; Osteopetrosis, intermediate forms; Osteopetrosis with renal tubular acidosis; Osteopetrosis, late-onset form type 1; Osteopetrosis, late-onset form type 2; Osteopetrosis, osteoclast poor
GWAS
Acute anterior uveitis in ankylosing spondylitis (
32492107
)
Refractive error (
32231278
)
Interacting Genes
71 interacting genes:
ADGRB3
ADGRE2
ARV1
ATP13A1
BNIP3
CACNG1
CCDC167
CDIPT
CHPT1
CLCN7
CLEC7A
CMTM5
COMT
CTXN3
CXCL16
CYP4F2
CYP4F22
DHRSX
EBP
EMC6
EMP1
ERG28
FA2H
FDFT1
FXYD6
FXYD6-FXYD2
GJB2
GOSR2
GYPA
HMOX1
IGFBP5
KRT1
LNPEP
MS4A13
MYG1
NAT8
NDUFA3
NINJ1
NKG7
ORMDL1
PMP22
PRAF2
PRRT2
REEP6
SCAMP5
SCD
SEC22A
SEC22B
SERP1
SFXN1
SFXN3
SLC22A18
SLC41A1
SMAGP
STATH
STX12
SYNDIG1
SYNJ2BP
TIMM23
TMEM115
TMEM120B
TMEM19
TMEM229B
TMEM237
TMEM60
TMIE
TVP23B
UBE2J1
VEZT
YIPF1
YIPF4
17 interacting genes:
AQP7
CD53
CREB3
GDAP1
GET1
KCNN3
LHFPL5
LMNA
LYVE1
MTDH
OPRM1
OSTM1
PACS1
SLC38A7
SLC66A2
TLCD4
TMEM179B
Entrez ID
148534
1186
HPRD ID
08110
04103
Ensembl ID
ENSG00000152078
ENSG00000103249
Uniprot IDs
Q96MV1
P51798
PDB IDs
7BXU
7JM7
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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