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ORC1 and GOLGA6L9
Data Source:
BioGRID
(two hybrid)
ORC1
GOLGA6L9
Description
origin recognition complex subunit 1
golgin A6 family like 9
Image
No pdb structure
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Origin Recognition Complex
Nucleus
Nucleoplasm
Nuclear Origin Of Replication Recognition Complex
Cytosol
Molecular Function
DNA Binding
Chromatin Binding
DNA Replication Origin Binding
Protein Binding
ATP Binding
ATPase Activity
Metal Ion Binding
Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
DNA Replication
DNA Replication Initiation
Mitotic DNA Replication Checkpoint
Pathways
E2F-enabled inhibition of pre-replication complex formation
Activation of ATR in response to replication stress
Assembly of the ORC complex at the origin of replication
CDC6 association with the ORC:origin complex
CDT1 association with the CDC6:ORC:origin complex
Assembly of the pre-replicative complex
Orc1 removal from chromatin
Activation of the pre-replicative complex
G1/S-Specific Transcription
Drugs
Diseases
Patella dysplasias, including: Small patella syndrome (SPS); Nail-patella syndrome; Ear-patella-short statute syndrome
GWAS
Tourette syndrome (
30818990
)
Interacting Genes
23 interacting genes:
CDC45
CDC5L
CDC6
CDC7
CDK2
CDT1
DBF4
GOLGA2
GOLGA6L9
KAT7
MCM2
MCM4
MCM5
MCM6
MCM7
ORC2
ORC3
ORC4
ORC5
RB1
RPA2
SKP2
XPO1
215 interacting genes:
ANKRD11
ARHGAP9
ASXL1
ATP6V1G1
ATPAF2
ATXN7L2
AVPI1
BAG6
BAHD1
BANP
BCL6B
BHLHA9
BYSL
C1orf109
C1orf35
C22orf15
C3
CABP2
CATIP
CAVIN3
CBX8
CCDC116
CCDC120
CCDC146
CCDC185
CCDC187
CCHCR1
CDC37
CDC73
CDK18
CEP72
CEP95
CNNM3
CWF19L2
DAXX
DEF6
DENND5A
DES
DOCK2
DPF2
DUSP26
EAF1
EIF3D
ENKD1
FAAP20
FAM107A
FAM110A
FAM161A
FAM161B
FAM207A
FBXO28
FEM1A
FLYWCH1
FXN
GADD45GIP1
GAS2L2
GEM
GLIS2
GPANK1
GTF2B
HAPLN2
HBZ
HDAC4
HDAC7
HGS
HOXB5
HOXB9
HOXC8
IL16
INO80B
ISCU
JMY
JRK
KANK2
KCTD9
KLHL35
KRT1
KRT75
LAGE3
LENG1
LGALS4
LMO3
LMO4
LYSMD1
M1AP
MAB21L2
MBD3
MBD3L2
MFAP1
MOS
MRPL11
MYOZ3
NAB2
NDUFAF3
NSMF
NTAQ1
NXF1
NXT2
ORC1
PATZ1
PCDHB14
PHF1
PIN1
PKN1
PNMA5
POLL
POLR1C
POU6F2
PPP1R18
PRKAB2
PRPF18
PRPF31
PWWP2B
RANBP3L
RASSF10
RIN1
RLN1
RNF39
RNPS1
RTP5
SCAND1
SCNM1
SH2D4A
SHC3
SLIRP
SMARCD1
SMARCE1
SNAI1
SSX5
STAMBPL1
STK25
SUOX
SUV39H1
SUV39H2
TACO1
TBC1D30
TCEANC
TEAD4
THAP7
TJAP1
TLE5
TLX3
TMSB4X
TPRX1
TRAF3IP3
TRAF4
TRIM14
TSEN54
TSFM
TSGA10IP
TSPYL4
TTC23
TXN2
TYK2
UBASH3A
UBL4B
UBTFL1
USHBP1
USP2
VEZF1
WDR25
ZBTB16
ZBTB24
ZFHX3
ZFP1
ZGPAT
ZKSCAN3
ZMAT2
ZNF124
ZNF155
ZNF165
ZNF17
ZNF20
ZNF205
ZNF230
ZNF250
ZNF264
ZNF32
ZNF329
ZNF35
ZNF410
ZNF414
ZNF417
ZNF438
ZNF444
ZNF446
ZNF479
ZNF48
ZNF490
ZNF497
ZNF524
ZNF552
ZNF557
ZNF574
ZNF578
ZNF580
ZNF581
ZNF587
ZNF599
ZNF624
ZNF628
ZNF629
ZNF648
ZNF669
ZNF696
ZNF764
ZNF785
ZNF792
ZNF80
ZNF835
ZNF837
ZNF844
ZNHIT1
ZSCAN23
ZSCAN26
Entrez ID
4998
440295
HPRD ID
03544
Ensembl ID
ENSG00000085840
ENSG00000197978
Uniprot IDs
B7Z8H0
Q13415
Q96F82
A6NEM1
PDB IDs
5UJ7
5UJM
6P3W
7JPO
7JPP
7JPR
7JPS
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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