NRTN and GFRA1

Data Source:
BioGRID (pull down, pull down)
HPRD (in vivo, in vitro)

		NRTN	GFRA1
Description		neurturin	GDNF family receptor alpha 1
Image
GO Annotations	Cellular Component	Extracellular Region Axon	Multivesicular Body Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Receptor Complex Extracellular Exosome
	Molecular Function	Signaling Receptor Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding	Signaling Receptor Binding Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity
	Biological Process	MAPK Cascade Neural Crest Cell Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Axon Guidance Nerve Development Neuron Projection Development	MAPK Cascade Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway
Pathways		NCAM1 interactions RAF/MAP kinase cascade RET signaling	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Chronotype ( 30696823) N-glycan levels ( 21908519 21203500 31163085)	Blood protein levels ( 30072576 29875488) Delirium ( 29631748) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Malaria ( 31844061) Migraine without aura ( 28952330) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
Interacting Genes		3 interacting genes: GFRA1 GFRA2 RET	5 interacting genes: GDNF NCAM1 NRTN RET SOCS3
Entrez ID		4902	2674
HPRD ID		03604	03291
Ensembl ID		ENSG00000171119	ENSG00000151892
Uniprot IDs		Q99748	B7Z856 P56159
PDB IDs		5MR4 5MR5 5MR9 5NMZ 6GL7 6Q2O 6Q2R	6Q2N
Enriched GO Terms of Interacting Partners?
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