GFRA1 and NRTN

Data Source:
BioGRID (pull down, pull down)
HPRD (in vivo, in vitro)

		GFRA1	NRTN
Description		GDNF family receptor alpha 1	neurturin
Image
GO Annotations	Cellular Component	Multivesicular Body Golgi Apparatus Plasma Membrane External Side Of Plasma Membrane Extrinsic Component Of Membrane Anchored Component Of Membrane Receptor Complex Extracellular Exosome	Extracellular Region Axon
	Molecular Function	Signaling Receptor Binding Glial Cell-derived Neurotrophic Factor Receptor Activity Signaling Receptor Activity	Signaling Receptor Binding Growth Factor Activity Glial Cell-derived Neurotrophic Factor Receptor Binding Receptor Tyrosine Kinase Binding
	Biological Process	MAPK Cascade Cell Surface Receptor Signaling Pathway Nervous System Development Axon Guidance Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway	MAPK Cascade Neural Crest Cell Migration Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Nervous System Development Axon Guidance Nerve Development Neuron Projection Development
Pathways		NCAM1 interactions RAF/MAP kinase cascade RET signaling	NCAM1 interactions RAF/MAP kinase cascade RET signaling
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Delirium ( 29631748) Epilepsy and lamotrigine-induced maculopapular eruptions ( 26220383) Malaria ( 31844061) Migraine without aura ( 28952330) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)	Advanced age-related macular degeneration ( 26691988) Blood protein levels ( 29875488) Chronotype ( 30696823) N-glycan levels ( 21908519 21203500 31163085)
Interacting Genes		5 interacting genes: GDNF NCAM1 NRTN RET SOCS3	3 interacting genes: GFRA1 GFRA2 RET
Entrez ID		2674	4902
HPRD ID		03291	03604
Ensembl ID		ENSG00000151892	ENSG00000171119
Uniprot IDs		B7Z856 P56159	Q99748
PDB IDs		6Q2N	5MR4 5MR5 5MR9 5NMZ 6GL7 6Q2O 6Q2R
Enriched GO Terms of Interacting Partners?
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