PYY and NPY1R

Data Source:
HPRD (in vivo)

		PYY	NPY1R
Description		peptide YY	neuropeptide Y receptor Y1
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding	Peptide YY Receptor Activity Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Feeding Behavior Intestinal Epithelial Cell Differentiation	Outflow Tract Morphogenesis Glucose Metabolic Process G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Locomotory Behavior Feeding Behavior Regulation Of Blood Pressure Sensory Perception Of Pain Regulation Of Multicellular Organism Growth
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Peptide YY (3-36)
Diseases
GWAS		Blood protein levels ( 30072576) Diverticular disease ( 30177863) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Pulse pressure ( 28135244) Response to taxane treatment (placlitaxel) ( 23006423) Triglyceride levels ( 32203549)	Erythrocyte cadmium concentration ( 27005419) Lung cancer ( 28604730) Metabolite levels ( 23823483) Triglyceride levels ( 30108155)
Interacting Genes		6 interacting genes: MEP1B NPY1R NPY2R NPY4R NPY5R SGTA	4 interacting genes: ATP13A2 LSM7 NPY PYY
Entrez ID		5697	4886
HPRD ID		02869	01215
Ensembl ID		ENSG00000131096	ENSG00000164128
Uniprot IDs		P10082	P25929
PDB IDs		2DEZ 2DF0 2L60 2NA5	2F1U 2IIL 5ZBQ
Enriched GO Terms of Interacting Partners?
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