NQO2 and DDIT4L

Data Source:
BioGRID (two hybrid)

		NQO2	DDIT4L
Description		N-ribosyldihydronicotinamide:quinone reductase 2	DNA damage inducible transcript 4 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Cytoplasm
	Molecular Function	Dihydronicotinamide Riboside Quinone Reductase Activity NAD(P)H Dehydrogenase (quinone) Activity Protein Binding Zinc Ion Binding Electron Transfer Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On Other Nitrogenous Compounds As Donors Chloride Ion Binding Protein Homodimerization Activity FAD Binding Melatonin Binding Resveratrol Binding	Protein Binding
	Biological Process	Xenobiotic Metabolic Process Memory Electron Transport Chain Positive Regulation Of Neuron Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Reactive Oxygen Species Metabolic Process	Negative Regulation Of Signal Transduction
Pathways		Phase I - Functionalization of compounds
Drugs		NADH Menadione Melatonin Primaquine Resveratrol Flavin adenine dinucleotide 10-Propargyl-5,8-Dideazafolic Acid Quercetin Tretazicar (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione N-[2-(2-iodo-5-methoxy-1H-indol-3-yl)ethyl]acetamide 5,8-dimethoxy-1,4-dimethylquinolin-2(1H)-one Casimiroin
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Urinary metabolite levels in chronic kidney disease ( 31959995)	Alcohol consumption (drinks per week) ( 30643258) Nose size ( 27182965)
Interacting Genes		7 interacting genes: DDIT4L DGCR6 EFHC1 GORASP2 IL32 LRRC7 SPG21	154 interacting genes: ABCB11 ACY3 AFMID AIDA AKT1 ARPIN BAG4 BANF2 BCL2L14 BID C14orf119 C18orf25 C19orf25 C5orf22 CABP5 CALCOCO2 CALM1 CALM2 CALM3 CATIP CCNK CDA CDKN2D CDPF1 CHMP1A CLIC3 CLK2 CLK3 CPNE7 CRLF3 CRYBB1 DBI DNPH1 DUSP23 DUSP29 EIF4A3 EIF4EBP1 EIF4H EPHB6 EXOSC1 EXOSC5 EXOSC8 FAAP20 FADD FHIT FHL2 FKBP6 FLNA GADD45G GEMIN6 GPKOW GRB2 GUCA1A HDAC7 HMG20A HSPB7 IL36RN IMPDH1 KANK2 KCTD9 KDM8 KRT34 KRTAP5-6 LENG1 LGALS14 LGALSL LMO1 LRATD2 LSM3 LSM5 LSM7 MAP3K7CL MAPRE2 MAPRE3 MEMO1 MIEN1 MKRN3 MLX MORF4L2 MT1M MYG1 MYLIP NAA10 NAV1 NEK6 NGB NHLRC4 NME7 NQO2 NR2C2AP NUDT2 NUDT22 NXT2 PARVG PCBP3 PDE4C PFKFB1 PLSCR4 PM20D2 PMVK PPCDC PPIL1 PPP1R27 PRKAB2 PRPF40A PSMA1 PSMB9 PTS PUF60 RAB32 RFC5 RFPL3 RPIA RPL22 RPRD1B SCOC SEC22A SEPTIN1 SEPTIN3 SEPTIN5 SH3BGRL3 SNRPA SNRPG SREK1IP1 STK16 STK4 SULT2B1 TBC1D22B TCL1A TCP11L1 TEKT4 TEX14 TFPT TNS2 TOLLIP TRIM73 TSEN15 TSSK3 TTC5 TXN TXNL4A TYW3 UBASH3A UBTFL1 VBP1 VCX2 YES1 YOD1 YPEL5 ZBED8 ZNF593 ZNF76 ZNF765 ZSCAN23
Entrez ID		4835	115265
HPRD ID		01190	09663
Ensembl ID		ENSG00000124588	ENSG00000145358
Uniprot IDs		B3KPX6 P16083 Q5TD07	Q96D03
PDB IDs		1QR2 1SG0 1XI2 1ZX1 2BZS 2QMY 2QMZ 2QR2 2QWX 2QX4 2QX6 2QX8 2QX9 3FW1 3G5M 3GAM 3NFR 3NHF 3NHJ 3NHK 3NHL 3NHP 3NHR 3NHS 3NHU 3NHW 3NHY 3O2N 3O73 3OVM 3OWH 3OWX 3OX1 3OX2 3OX3 3TE7 3TEM 3TZB 3UXE 3UXH 4FGJ 4FGK 4FGL 4GQI 4GR9 4QOD 4QOE 4QOF 4QOG 4QOH 4QOI 4QOJ 4U7F 4U7G 4U7H 4XDG 4XDH 4ZVK 4ZVL 4ZVM 4ZVN 5BUC 5LBT 5LBU 5LBW 5LBY 5LBZ
Enriched GO Terms of Interacting Partners?
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