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NME1 and FXR2
Data Source:
BioGRID
(two hybrid)
NME1
FXR2
Description
NME/NM23 nucleoside diphosphate kinase 1
FMR1 autosomal homolog 2
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Centrosome
Cytosol
Intermediate Filament
Membrane
Ruffle Membrane
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Nucleus
Cytoplasm
Cytosol
Polysome
Postsynaptic Density
Membrane
Cytosolic Large Ribosomal Subunit
Axon
Growth Cone
Cytoplasmic Ribonucleoprotein Granule
Neuronal Cell Body
Dendritic Spine
Dendritic Spine Neck
Presynapse
Dendritic Filopodium
Molecular Function
Magnesium Ion Binding
RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
Single-stranded DNA Binding
RNA Binding
Deoxyribonuclease Activity
Nucleoside Diphosphate Kinase Activity
Protein Binding
ATP Binding
GTP Binding
Intermediate Filament Binding
Enzyme Binding
Identical Protein Binding
Gamma-tubulin Binding
Ribosomal Small Subunit Binding
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Translation Regulator Activity
Protein Heterodimerization Activity
Biological Process
Negative Regulation Of Myeloid Leukocyte Differentiation
Nucleoside Diphosphate Phosphorylation
GTP Biosynthetic Process
UTP Biosynthetic Process
CTP Biosynthetic Process
DNA Metabolic Process
Endocytosis
Lactation
Negative Regulation Of Cell Population Proliferation
Negative Regulation Of Gene Expression
Positive Regulation Of Neuron Projection Development
Response To Amine
Nucleobase-containing Small Molecule Interconversion
Hippocampus Development
Cell Differentiation
Response To Testosterone
Cellular Response To Drug
Regulation Of Apoptotic Process
Positive Regulation Of DNA Binding
Positive Regulation Of Epithelial Cell Proliferation
Response To CAMP
Cellular Response To Glucose Stimulus
Cellular Response To Fatty Acid
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Translation
Regulation Of MRNA Stability
Positive Regulation Of Translation
Regulation Of Filopodium Assembly
Positive Regulation Of Response To DNA Damage Stimulus
Pathways
Interconversion of nucleotide di- and triphosphates
Drugs
Zinc
2'-Deoxyguanosine-5'-Triphosphate
Selenocysteine
2',3'-Dehydro-2',3'-Deoxy-Thymidine 5'-Diphosphate
Adenosine Phosphonoacetic Acid
Stavudine triphosphate
Thymidine-5'- Diphosphate
2'-Deoxyguanosine-5'-Diphosphate
2',3'-dideoxy-3'-fluoro-urididine-5'-diphosphate
Guanosine-5'-Diphosphate
3'-Deoxy 3'-Amino Adenosine-5'-Diphosphate
Zidovudine diphosphate
Copper
Zinc acetate
Zinc chloride
Zinc sulfate, unspecified form
Diseases
GWAS
Bipolar disorder (
31043756
)
Conjunctival UV autofluorescence (CUVAF) (
25590795
)
Metabolite levels (
23823483
)
Atrial fibrillation (
30061737
)
Brain morphology (MOSTest) (
32665545
)
IgM levels (
23118916
)
Refractive error (
32231278
)
Sex hormone-binding globulin levels (
22675492
)
Interacting Genes
31 interacting genes:
APEX1
AURKA
CCND3
FBXO24
FXR2
GORASP2
ITGB1
KSR1
LNX1
MIF
NIF3L1
NME2
NME3
NME4
NTAQ1
NUTF2
PID1
POLR1C
PRUNE1
RAC1
RORA
RORB
RRAD
SET
SMARCD1
SOX30
SREK1IP1
TERF1
TIAM1
TNPO2
TNPO3
107 interacting genes:
AKAP9
AMOTL2
AP1M1
AP2M1
ARL6IP1
BAZ2B
BLK
BRCA1
BYSL
C10orf62
C1orf35
CALCOCO2
CBS
CCDC33
CCDC85B
CCR4
CDKL3
CEP44
CEP55
COIL
CWF19L2
CYFIP1
CYFIP2
DDX17
DMRTB1
DPPA2
DYNLT1
EIF4G1
EWSR1
FAM90A1
FBP1
FMR1
FTH1
FXR1
GKAP1
GTSE1
HMBOX1
HNRNPC
IGFN1
INPP5J
KCNRG
KCTD4
KIAA1217
KIF1A
KIF2A
KRT20
KXD1
LASP1
LCMT1
LCP2
LDOC1
MAPRE3
MBIP
MCRS1
MEAF6
MFAP1
MIA3
MORF4L1
MRPL43
NCK2
NDEL1
NDN
NECAB2
NEXN
NIF3L1
NME1
NONO
NT5C2
PAF1
PAICS
PCBD1
PCM1
PIM1
POM121
PRAM1
PRC1
PSME3
PTS
RABAC1
RALYL
RBBP8
RBM14
RBMX
RBPMS
RPIA
RTN3
RTN4
SCEL
SNAP23
SYT6
SYTL4
TBC1D22B
THAP1
TNNT1
TRAF2
TRIM23
TRIM29
TRIM37
TSC22D4
YES1
ZBTB22
ZBTB8A
ZMAT2
ZNF232
ZNF451
ZNRD2
ZSCAN1
Entrez ID
4830
9513
HPRD ID
01131
05629
Ensembl ID
ENSG00000239672
ENSG00000129245
Uniprot IDs
A0A384MTW7
P15531
P51116
PDB IDs
1JXV
1UCN
2HVD
2HVE
3L7U
4ENO
5UI4
3H8Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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