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FXR2 and AMOTL2
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
FXR2
AMOTL2
Description
FMR1 autosomal homolog 2
angiomotin like 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Polysome
Postsynaptic Density
Membrane
Cytosolic Large Ribosomal Subunit
Axon
Growth Cone
Cytoplasmic Ribonucleoprotein Granule
Neuronal Cell Body
Dendritic Spine
Dendritic Spine Neck
Presynapse
Dendritic Filopodium
Cytosol
Plasma Membrane
Bicellular Tight Junction
Cytoplasmic Vesicle
Recycling Endosome
Molecular Function
RNA Binding
MRNA 3'-UTR Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Translation Regulator Activity
Protein Heterodimerization Activity
Protein Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Translation
Regulation Of MRNA Stability
Positive Regulation Of Translation
Regulation Of Filopodium Assembly
Positive Regulation Of Response To DNA Damage Stimulus
Angiogenesis
Establishment Of Cell Polarity Involved In Ameboidal Cell Migration
Wnt Signaling Pathway
Actin Cytoskeleton Organization
Regulation Of Cell Migration
Hippo Signaling
Pathways
Signaling by Hippo
Drugs
Diseases
GWAS
Atrial fibrillation (
30061737
)
Brain morphology (MOSTest) (
32665545
)
IgM levels (
23118916
)
Refractive error (
32231278
)
Sex hormone-binding globulin levels (
22675492
)
Cadmium levels (
26025379
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Reticulocyte fraction of red cells (
32888494
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Vertical cup-disc ratio (adjusted for vertical disc diameter) (
31959993
)
Interacting Genes
107 interacting genes:
AKAP9
AMOTL2
AP1M1
AP2M1
ARL6IP1
BAZ2B
BLK
BRCA1
BYSL
C10orf62
C1orf35
CALCOCO2
CBS
CCDC33
CCDC85B
CCR4
CDKL3
CEP44
CEP55
COIL
CWF19L2
CYFIP1
CYFIP2
DDX17
DMRTB1
DPPA2
DYNLT1
EIF4G1
EWSR1
FAM90A1
FBP1
FMR1
FTH1
FXR1
GKAP1
GTSE1
HMBOX1
HNRNPC
IGFN1
INPP5J
KCNRG
KCTD4
KIAA1217
KIF1A
KIF2A
KRT20
KXD1
LASP1
LCMT1
LCP2
LDOC1
MAPRE3
MBIP
MCRS1
MEAF6
MFAP1
MIA3
MORF4L1
MRPL43
NCK2
NDEL1
NDN
NECAB2
NEXN
NIF3L1
NME1
NONO
NT5C2
PAF1
PAICS
PCBD1
PCM1
PIM1
POM121
PRAM1
PRC1
PSME3
PTS
RABAC1
RALYL
RBBP8
RBM14
RBMX
RBPMS
RPIA
RTN3
RTN4
SCEL
SNAP23
SYT6
SYTL4
TBC1D22B
THAP1
TNNT1
TRAF2
TRIM23
TRIM29
TRIM37
TSC22D4
YES1
ZBTB22
ZBTB8A
ZMAT2
ZNF232
ZNF451
ZNRD2
ZSCAN1
91 interacting genes:
AMOT
BFSP2
BLZF1
BRMS1L
BYSL
CARD9
CCDC185
CCDC196
CCDC57
CCHCR1
CDC37
CDR2
CHCHD3
CINP
CYTH4
DAXX
DDIT3
DTNB
DYNLL1
DZIP1L
EIF4E2
FAM184A
FAM90A1
FBXO7
FCRL5
FXR2
GCC1
GNG11
GNG5
GOLGA2
GSTM5
KIF9
KRT1
KRT13
KRT15
KRT19
KRT20
KRT31
KRT38
KRTAP10-5
KRTAP4-2
L3MBTL2
LMNB2
LMO3
LMO4
MAD1L1
MAGEA4
MAGOHB
MFAP1
MORF4L2
MPP1
MTMR6
MTNR1A
MYO5B
NDC80
NF2
NFIL3
NME7
NTAQ1
PIBF1
PPP2CA
PPP2R1A
PRKAA2
PRPF18
PSMC3
RAD51D
RALBP1
RASAL3
RASSF5
RNF20
RNF40
RNF8
SAAL1
SH3RF2
SMARCE1
SOGA1
SP100
SPAG5
SPOP
SPP1
TCEA2
THRA
TMCC2
TNKS2
TRAF2
TRIM27
TSGA10IP
YES1
ZBED1
ZBTB16
ZGPAT
Entrez ID
9513
51421
HPRD ID
05629
16485
Ensembl ID
ENSG00000129245
ENSG00000114019
Uniprot IDs
P51116
Q9Y2J4
PDB IDs
3H8Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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