ATP1B3 and MYCBP2

Data Source:
BioGRID (affinity chromatography technology)

		ATP1B3	MYCBP2
Description		ATPase Na+/K+ transporting subunit beta 3	MYC binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton Membrane Axon Intracellular Membrane-bounded Organelle
	Molecular Function	ATPase Activator Activity Protein Binding Protein-macromolecule Adaptor Activity ATPase Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Small GTPase Binding Identical Protein Binding Ubiquitin Protein Ligase Activity
	Biological Process	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Across Plasma Membrane Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Protein Ubiquitination Branchiomotor Neuron Axon Guidance Central Nervous System Projection Neuron Axonogenesis Positive Regulation Of Protein Ubiquitination Regulation Of Protein Localization Circadian Regulation Of Gene Expression Negative Regulation Of Protein Catabolic Process Regulation Of Catalytic Activity Neuromuscular Process Regulation Of Cytoskeleton Organization Regulation Of Axon Guidance
Pathways		Basigin interactions Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Pulse pressure ( 27841878) Red cell distribution width ( 32888494 27863252 28957414) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196) White blood cell count ( 32888494)	Chronotype ( 30696823) Iris heterochromicity ( 30895295) Morning person ( 30696823) Preeclampsia ( 23551011) Tourette's syndrome or obsessive-compulsive disorder ( 25158072)
Interacting Genes		13 interacting genes: BAALC BARD1 BRCA1 CTXN3 NLRP3 PAXIP1 PEA15 SMAGP STOM TMEM98 TRIM14 UPF2 USP4	15 interacting genes: APPL1 ATP13A2 CALM1 ERBB3 FBXO45 MYC NMNAT2 PTPN12 SRPK2 TTN UBE2D2 UBE2D3 UBE2L3 YWHAG YWHAQ
Entrez ID		483	23077
HPRD ID		03521	10104
Ensembl ID		ENSG00000069849	ENSG00000005810
Uniprot IDs		P54709	O75592
PDB IDs			5O6C 6T7F
Enriched GO Terms of Interacting Partners?
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