CCT7 and CRMP1

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CCT7	CRMP1
Description		chaperonin containing TCP1 subunit 7	collapsin response mediator protein 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol Chaperonin-containing T-complex Microtubule Cell Body Extracellular Exosome	Nucleus Centrosome Spindle Cytosol Growth Cone Midbody Perikaryon
	Molecular Function	Protein Binding ATP Binding Identical Protein Binding Protein Folding Chaperone Unfolded Protein Binding	Dihydropyrimidinase Activity Protein Binding Filamin Binding Identical Protein Binding
	Biological Process	Protein Folding Binding Of Sperm To Zona Pellucida Positive Regulation Of Telomere Maintenance Via Telomerase Protein Stabilization Toxin Transport Positive Regulation Of Establishment Of Protein Localization To Telomere Positive Regulation Of Protein Localization To Cajal Body Positive Regulation Of Telomerase RNA Localization To Cajal Body	Microtubule Cytoskeleton Organization Nucleobase-containing Compound Metabolic Process Pyrimidine Nucleobase Catabolic Process Nervous System Development Axon Guidance Negative Regulation Of Neuron Projection Development Negative Regulation Of Actin Filament Binding
Pathways		Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Folding of actin by CCT/TriC Association of TriC/CCT with target proteins during biosynthesis Association of TriC/CCT with target proteins during biosynthesis Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding	CRMPs in Sema3A signaling
Drugs
Diseases
GWAS		General cognitive ability ( 29844566)	Blood trace element (Zn levels) ( 23720494) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Metabolite levels ( 23823483) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		22 interacting genes: ANXA1 ANXA7 APP ATP5F1C CDKN1A CEBPE CRMP1 DNM2 EEF1G KAT5 KRAS LINC01554 MED31 NHLH1 NKX3-1 PRPF40A RAP1B RCC1 SUMO4 TCP1 WBP2 ZNRD2	80 interacting genes: AGR2 ALDH2 AMFR ANXA7 AP3M1 ARL15 AXIN1 BID BTBD2 CACNA1A CCDC106 CCL18 CCT7 CDK5RAP2 CDK5RAP3 DDX18 DNAJB11 DPYSL2 DPYSL3 DUSP4 EEF1D EIF2S2 EPN1 EXOSC8 FAS FTH1 FUBP1 FXR1 GNE GOLGA2 HDHD2 HGS HMGB1 HNRNPH1 HNRNPH3 HNRNPUL1 HSPE1 HTT IL33 KLHL20 LRRC1 LRRK2 LSM2 MAP3K20 MAPK8IP2 MCM3AP MOB4 MRPS12 NAT9 NDUFV2 NVL PAFAH1B3 PFN1 PLA2G2A PMF1 PPP1R8 PSMD11 RACK1 RGL2 RGS2 ROCK1 RPA2 RPS6KA5 RTN4 SAT1 SEPHS1 SERPINB9 SNRPG SPRY2 SRC TFG TK1 TRIP13 TSC22D1 UBE2A UBE2B VCP VIM YAE1 ZNF24
Entrez ID		10574	1400
HPRD ID		06896	03913
Ensembl ID		ENSG00000135624	ENSG00000072832
Uniprot IDs		Q99832	B3KT07 B3KV96 E9PD68 Q14194 Q96I11 X5DNI1
PDB IDs		6NR8 6NR9 6NRA 6NRB 6NRC 6NRD 6QB8	4B3Z
Enriched GO Terms of Interacting Partners?
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