NFKBIE and PEX6

Data Source:
BioGRID (genetic interference)

		NFKBIE	PEX6
Description		NFKB inhibitor epsilon	peroxisomal biogenesis factor 6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Perinuclear Region Of Cytoplasm	Photoreceptor Outer Segment Cytoplasm Peroxisome Peroxisomal Membrane Cytosol Photoreceptor Cell Cilium
	Molecular Function	Protein Binding	Protein Binding ATP Binding Protein C-terminus Binding ATPase Activity Protein-containing Complex Binding
	Biological Process	D-serine Transport Cytoplasmic Sequestering Of Transcription Factor	Protein Targeting To Peroxisome Peroxisome Organization Protein Import Into Peroxisome Matrix Protein Import Into Peroxisome Matrix, Translocation Protein Stabilization
Pathways		Activation of NF-kappaB in B cells	Peroxisomal protein import Peroxisomal protein import
Drugs
Diseases		Hodgkin lymphoma	Zellweger syndrome spectrum, including: Zellweger syndrome (ZS); Adrenoleukodystrophy, neonatal (NALD); Infantile Refsum disease (IRD)
GWAS		Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Rheumatoid arthritis ( 30423114 22446963 23028356 24390342)	Alzheimer's disease in APOE e4+ carriers ( 25778476) Hematocrit ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		15 interacting genes: ANKHD1 C1QBP CUL1 HDAC4 HDAC5 IL1A JUP KBTBD7 NCOR2 NFKB1 NFKB2 PPP6C REL RELA SKP1	8 interacting genes: ATF7IP CERS2 PEX1 PEX26 PEX5 RPL27A RPS14 SMAD3
Entrez ID		4794	5190
HPRD ID		05181	03293
Ensembl ID		ENSG00000146232	ENSG00000124587
Uniprot IDs		A0A024RD24 O00221 Q7LC14 Q96F31	A0A024RD09 Q13608
PDB IDs
Enriched GO Terms of Interacting Partners?
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