Wiki-MPM

  • About
  • Search
  • Browse
  • People
  • Funding
  • Updates

MLKL

Description mixed lineage kinase domain like pseudokinase
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
  • Plasma Membrane
  • Cell Junction
Molecular Function
  • Protein Kinase Activity
  • JUN Kinase Kinase Kinase Activity
  • Protein Binding
  • ATP Binding
  • Protein Kinase Binding
  • Protein-containing Complex Binding
Biological Process
  • Protein Phosphorylation
  • Cell Surface Receptor Signaling Pathway
  • Activation Of JNKK Activity
  • Activation Of JUN Kinase Activity
  • Defense Response To Virus
  • Protein Homotrimerization
  • Necroptotic Process
  • Necroptotic Signaling Pathway
  • Execution Phase Of Necroptosis
Pathways
  • TRP channels
  • RIPK1-mediated regulated necrosis
  • Regulation of necroptotic cell death
  • Microbial modulation of RIPK1-mediated regulated necrosis
Drugs
Diseases
GWAS
  • Testicular germ cell tumor ( 23666239)
Novel Interacting Genes 1 novel interacting genes: PMFBP1
Interacting Genes 7 interacting genes: ANAPC11 CDK1 NDUFB7 PSMB1 RAD18 S100A10 THOC3
Entrez ID 197259
HPRD ID 08752
Ensembl ID ENSG00000168404
Uniprot IDs Q8NB16
PDB IDs 2MSV 4M67 4MWI 5KNJ 5KO1 6BWK 6D74 6O5Z 6UX8
Enriched GO Terms of Interacting Partners?
Tagcloud ?

© Madhavi K. Ganapathiraju 2012-2025