ACLY and DDIAS

Data Source:
BioGRID (two hybrid)

		ACLY	DDIAS
Description		ATP citrate lyase	DNA damage induced apoptosis suppressor
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Cellular_component Nucleus Cytoplasm
	Molecular Function	ATP Citrate Synthase Activity Protein Binding ATP Binding Metal Ion Binding	Molecular_function
	Biological Process	Acetyl-CoA Biosynthetic Process Citrate Metabolic Process Oxaloacetate Metabolic Process Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Lipid Biosynthetic Process Coenzyme A Metabolic Process Positive Regulation Of Cellular Metabolic Process Neutrophil Degranulation Fatty-acyl-CoA Biosynthetic Process	Apoptotic Process Mitotic Cell Cycle Arrest Regulation Of DNA Stability Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Pathways		ChREBP activates metabolic gene expression Neutrophil degranulation Fatty acyl-CoA biosynthesis
Drugs		Bempedoic acid
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes		8 interacting genes: APP CDKN2A CUL3 DDIAS GSK3B HGS KLHL25 PRKACA	10 interacting genes: ACLY ACTN1 ACTN4 CBY1 ECM1 EFEMP1 FBLN1 MAF1 MIF4GD PLSCR1
Entrez ID		47	220042
HPRD ID		00155	08062
Ensembl ID		ENSG00000131473	ENSG00000165490
Uniprot IDs		A0A024R1T9 A0A024R1Y2 P53396 Q4LE36	B4DMA1 Q8IXT1
PDB IDs		3MWD 3MWE 3PFF 5TDE 5TDF 5TDM 5TDZ 5TE1 5TEQ 5TES 5TET 6HXH 6HXK 6HXL 6HXM 6O0H 6POE 6POF 6QFB 6UI9 6UIA 6UUW 6UUZ 6UV5
Enriched GO Terms of Interacting Partners?
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