ACLY

Description		ATP citrate lyase
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GO Annotations	Cellular Component	Extracellular Region Nucleoplasm Cytosol Plasma Membrane Membrane Azurophil Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	ATP Citrate Synthase Activity Protein Binding ATP Binding Metal Ion Binding
	Biological Process	Acetyl-CoA Biosynthetic Process Citrate Metabolic Process Oxaloacetate Metabolic Process Fatty Acid Biosynthetic Process Cholesterol Biosynthetic Process Lipid Biosynthetic Process Coenzyme A Metabolic Process Positive Regulation Of Cellular Metabolic Process Neutrophil Degranulation Fatty-acyl-CoA Biosynthetic Process
Pathways		ChREBP activates metabolic gene expression Neutrophil degranulation Fatty acyl-CoA biosynthesis
Drugs		Bempedoic acid
Diseases
GWAS		High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes		8 interacting genes: APP CDKN2A CUL3 DDIAS GSK3B HGS KLHL25 PRKACA
Entrez ID		47
HPRD ID		00155
Ensembl ID		ENSG00000131473
Uniprot IDs		A0A024R1T9 A0A024R1Y2 P53396 Q4LE36
PDB IDs		3MWD 3MWE 3PFF 5TDE 5TDF 5TDM 5TDZ 5TE1 5TEQ 5TES 5TET 6HXH 6HXK 6HXL 6HXM 6O0H 6POE 6POF 6QFB 6UI9 6UIA 6UUW 6UUZ 6UV5
Enriched GO Terms of Interacting Partners?
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