ATF4 and GABBR2

  • Data Source:
  • HPRD (two hybrid)

ATF4

GABBR2

Description activating transcription factor 4 gamma-aminobutyric acid type B receptor subunit 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028)
  • Inflammatory bowel disease ( 23128233)
  • Mean corpuscular volume ( 32888494)
  • Gynecologic disease (multivariate analysis) ( 31488892)
  • High chromosomal aberration frequency (chromatid type) ( 31586183)
  • Post-traumatic stress disorder (asjusted for relatedness) ( 23726511)
  • Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Response to simvastatin treatment (PCSK9 protein level change) ( 25089948)
  • Response to TNF inhibitor in rheumatoid arthritis (change in tender 28-joint count) ( 30166627)
  • Schizophrenia ( 30285260)
  • Systolic blood pressure change trajectories ( 27980656)
Interacting Genes 75 interacting genes: AP1M1 APH1A APP ASB7 ATF2 ATF3 BATF BATF2 BATF3 BFSP2 BTRC CCDC106 CEBPA CEBPB CEBPE CEBPG CEP83 CKAP4 CREB3 CREBBP CREBZF DAPK3 DDIT3 DISC1 DNMT3L EGLN3 EP300 FOS FOSL1 GABBR2 GCC1 GOLGA1 GOLGA8EP GOLGA8F GPS2 GTF2A1L GTF2B GTF2F2 HAUS7 HK3 JDP2 JUN JUNB KAT2B LDOC1 LMNB1 MAF MAFB MAP2K7 MDM2 MPZL2 NAP1L5 NDC80 NEK6 NFE2 NFE2L1 NFE2L2 NFKBIA NLGN3 POLR2C PTCD3 REPS1 RPS6 SAPCD2 SNAP29 SRA1 TARS3 TBP TGM2 TREX2 TRIB3 TRIM24 TTR ZNF212 ZNF226 11 interacting genes: ATF4 ATF5 DRD2 GABBR1 GLP1R HTR1A KCTD12 KCTD16 NSF SH3GL3 TAMALIN
Entrez ID 468 9568
HPRD ID 06817 09552
Ensembl ID ENSG00000128272 ENSG00000136928
Uniprot IDs P18848 H9NIL8 O75899
PDB IDs 1CI6 4F11 4F12 4MQE 4MQF 4MR7 4MR8 4MR9 4MRM 4MS1 4MS3 4MS4 4PAS 6M8R 6OCP 6UO8 6UO9 6UOA 6VJM 6W2X 6WIV 7C7Q 7C7S
Enriched GO Terms of Interacting Partners?
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