MYL1 and ANKRD1

Data Source:
BioGRID (two hybrid)

		MYL1	ANKRD1
Description		myosin light chain 1	ankyrin repeat domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Muscle Myosin Complex Myofibril Sarcomere	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol I Band
	Molecular Function	Calcium Ion Binding Structural Constituent Of Muscle	RNA Polymerase II Transcription Factor Binding P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding
	Biological Process	Muscle Contraction Muscle Filament Sliding Cardiac Muscle Contraction	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Regulation Of Lipid Metabolic Process Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process
Pathways		Striated Muscle Contraction	PPARA activates gene expression
Drugs
Diseases
GWAS		Serum metabolite levels ( 23093944)	Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)
Interacting Genes		7 interacting genes: ACTA1 ACTA2 ANKRD1 APP EPB41 IQGAP1 UBC	23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446
Entrez ID		4632	27063
HPRD ID		01180	10647
Ensembl ID		ENSG00000168530	ENSG00000148677
Uniprot IDs		P05976	A0A384NYH5 Q15327
PDB IDs
Enriched GO Terms of Interacting Partners?
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