ANKRD1 and MYPN

Data Source:
BioGRID (pull down)
HPRD (two hybrid)

		ANKRD1	MYPN
Description		ankyrin repeat domain 1	myopalladin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Fibrillar Center Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol I Band	Nucleus Plasma Membrane Z Disc Axon I Band
	Molecular Function	RNA Polymerase II Transcription Factor Binding P53 Binding DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Titin Binding Histone Deacetylase Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding R-SMAD Binding	Actin Binding Protein Binding Cytoskeletal Protein Binding SH3 Domain Binding Muscle Alpha-actinin Binding Cell-cell Adhesion Mediator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Neuron Projection Development Regulation Of Lipid Metabolic Process Cellular Response To Drug Skeletal Muscle Cell Differentiation Response To Muscle Stretch Positive Regulation Of Apoptotic Process Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Sarcomere Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Protein Secretion Cardiac Muscle Tissue Morphogenesis Protein Kinase C Signaling Cellular Response To Lipopolysaccharide Cellular Response To Mechanical Stimulus Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Cellular Response To Organic Cyclic Compound Cellular Response To Hypoxia Cellular Response To Transforming Growth Factor Beta Stimulus Negative Regulation Of DNA Biosynthetic Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Axon Guidance Sarcomere Organization Dendrite Self-avoidance
Pathways		PPARA activates gene expression
Drugs
Diseases
GWAS		Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Refractive error ( 32231278)	Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737) Chronic kidney disease ( 31152163) Coffee consumption ( 31046077) Creatine kinase levels ( 29403010) Creatinine levels ( 29403010) Estimated glomerular filtration rate ( 31152163 31015462 31451708 30604766) Estimated glomerular filtration rate in non-diabetics ( 31451708) FEV1 ( 30804560) Glomerular filtration rate ( 29403010) Height ( 25282103) Lung function (FVC) ( 28166213 30804560) Optic nerve measurement (disc area) ( 20395239) Peak expiratory flow ( 30804560) Psoriasis ( 25854761)
Interacting Genes		23 interacting genes: APPL1 ARHGDIB ASH2L CASQ2 CDCA7L DNAJB6 DST DYSF LRPPRC MAPRE3 MEOX2 MYBPC1 MYL1 MYOM2 MYPN NAGK REPS1 SPANXN2 TRIM55 TRIM63 TTN TULP3 ZNF446	8 interacting genes: ACTN2 ACTN3 ANKRD1 ANKRD23 NEB NEBL PDLIM3 TTN
Entrez ID		27063	84665
HPRD ID		10647	10536
Ensembl ID		ENSG00000148677	ENSG00000138347
Uniprot IDs		A0A384NYH5 Q15327	A0A087WX60 Q86TC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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