Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ANKRD1 and ASH2L
Data Source:
BioGRID
(two hybrid)
ANKRD1
ASH2L
Description
ankyrin repeat domain 1
ASH2 like, histone lysine methyltransferase complex subunit
Image
No pdb structure
GO Annotations
Cellular Component
Fibrillar Center
Nucleus
Nucleoplasm
Transcription Regulator Complex
Cytoplasm
Cytosol
I Band
Nucleus
Nucleoplasm
Histone Methyltransferase Complex
MLL3/4 Complex
Set1C/COMPASS Complex
Molecular Function
RNA Polymerase II Transcription Factor Binding
P53 Binding
DNA Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Titin Binding
Histone Deacetylase Binding
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
R-SMAD Binding
Transcription Regulatory Region Sequence-specific DNA Binding
Protein Binding
Beta-catenin Binding
Histone Methyltransferase Activity (H3-K4 Specific)
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Neuron Projection Development
Regulation Of Lipid Metabolic Process
Cellular Response To Drug
Skeletal Muscle Cell Differentiation
Response To Muscle Stretch
Positive Regulation Of Apoptotic Process
Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator
Sarcomere Organization
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Protein Secretion
Cardiac Muscle Tissue Morphogenesis
Protein Kinase C Signaling
Cellular Response To Lipopolysaccharide
Cellular Response To Mechanical Stimulus
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Organic Cyclic Compound
Cellular Response To Hypoxia
Cellular Response To Transforming Growth Factor Beta Stimulus
Negative Regulation Of DNA Biosynthetic Process
Cellular Response To DNA Damage Stimulus
Positive Regulation Of Cell Population Proliferation
Hemopoiesis
Response To Estrogen
Regulation Of Megakaryocyte Differentiation
Histone H3-K4 Methylation
Beta-catenin-TCF Complex Assembly
Pathways
PPARA activates gene expression
Formation of the beta-catenin:TCF transactivating complex
PKMTs methylate histone lysines
Deactivation of the beta-catenin transactivating complex
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Intraocular pressure (
29617998
)
Refractive error (
32231278
)
Menopause (age at onset) (
22267201
)
Schizophrenia (
29483656
)
Interacting Genes
23 interacting genes:
APPL1
ARHGDIB
ASH2L
CASQ2
CDCA7L
DNAJB6
DST
DYSF
LRPPRC
MAPRE3
MEOX2
MYBPC1
MYL1
MYOM2
MYPN
NAGK
REPS1
SPANXN2
TRIM55
TRIM63
TTN
TULP3
ZNF446
37 interacting genes:
ACTC1
ACTN2
ANKRD1
BARD1
BRCA1
CCNC
CEP76
CHD8
COPS6
CTNNB1
DNMT3L
DPY30
EP300
H3-4
H3C1
KMT2A
KMT2B
KMT2D
KMT2E
MEN1
MESD
MKRN1
MYBPC1
MYOM3
PPP1CC
PRMT1
RBBP5
SMAD9
SMURF1
SMURF2
TGFBR1
TP53
TTN
UNC119
WDR5
WWP1
ZSCAN1
Entrez ID
27063
9070
HPRD ID
10647
05309
Ensembl ID
ENSG00000148677
ENSG00000129691
Uniprot IDs
A0A384NYH5
Q15327
B4DPT1
F5H8F7
Q9UBL3
PDB IDs
3RSN
3S32
3TOJ
4RIQ
4X8N
4X8P
5F6K
5F6L
6E2H
6KIU
6KIV
6KIW
6KIX
6KIZ
6PWV
7BRE
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?