MT-CYB and MVP

Data Source:
BioGRID (two hybrid)

		MT-CYB	MVP
Description		cytochrome b	major vault protein
Image
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Intrinsic Component Of Membrane Integral Component Of Mitochondrial Inner Membrane	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Ubiquinol-cytochrome-c Reductase Activity Protein-containing Complex Binding Metal Ion Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding
	Biological Process	Response To Hypoxia Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Response To Heat Response To Toxic Substance Electron Transport Coupled Proton Transport Animal Organ Regeneration Response To Cobalamin Response To Glucagon Response To Drug Hyperosmotic Salinity Response Response To Ethanol Response To Cadmium Ion Response To Copper Ion Response To Mercury Ion Response To Calcium Ion Response To Hyperoxia	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neutrophil Degranulation MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity
Pathways		Respiratory electron transport	Neutrophil degranulation
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 6-Hydroxy-5-undecyl-4,7-benzothiazoledione Azoxystrobin 5-Heptyl-6-hydroxy-1,3-benzothiazole-4,7-dione (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE (S)-famoxadone METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-Nonyl-4-quinolinol 1-oxide Ubiquinone Q2
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Interacting Genes		2 interacting genes: KRAS MVP	64 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DTX2 EPHX2 ESR1 FNDC3B GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2
Entrez ID		4519	9961
HPRD ID		02468	05475
Ensembl ID		ENSG00000198727	ENSG00000013364
Uniprot IDs		P00156 Q0ZFD6 Q6VLV1	Q14764 X5D2M8 X5D7K9 X5DNU0
PDB IDs		5XTE 5XTH 5XTI	1Y7X
Enriched GO Terms of Interacting Partners?
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