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ASPH and PRH1
Data Source:
BioGRID
(two hybrid)
ASPH
PRH1
Description
aspartate beta-hydroxylase
proline rich protein HaeIII subfamily 1
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Membrane
Cortical Endoplasmic Reticulum
Sarcoplasmic Reticulum Membrane
Extracellular Space
Molecular Function
Peptide-aspartate Beta-dioxygenase Activity
Structural Molecule Activity
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Electron Transfer Activity
Peptidyl-aspartic Acid 3-dioxygenase Activity
Protein Binding
Biological Process
Muscle Contraction
Protein Phosphopantetheinylation
Electron Transport Chain
Ion Transmembrane Transport
Peptidyl-aspartic Acid Hydroxylation
Positive Regulation Of Proteolysis
Activation Of Cysteine-type Endopeptidase Activity
Regulation Of Cardiac Conduction
Pathways
Stimuli-sensing channels
Ion homeostasis
Drugs
Aspartic acid
Diseases
GWAS
Blood protein levels (
30072576
29875488
)
BRCA1/2-negative high-risk breast cancer (
30323354
)
Resting heart rate (
28270201
)
Serum omega-6 to omega-3 polyunsaturated fatty acid ratio in metabolic syndrome (
31991592
)
Urate levels in overweight individuals (
25811787
)
Interacting Genes
71 interacting genes:
AGR2
APP
BGLAP
CDSN
CHRM5
CST1
CTSA
CXorf66
DCD
DEFB1
DHRSX
ENPP6
FBXO7
FDCSP
FGFBP1
FKBP7
GAL
GAST
GET3
GOLM1
GPR119
GPX7
GPX8
GSC2
GUCA2A
IL21
INSL5
KCNIP1
KCNIP3
KCNIP4
LCN2
LRPAP1
LTA
NUCB2
OCIAD1
PCSK4
PDGFA
PDGFRL
PLAAT2
PLEKHF2
PRAP1
PRB1
PRB2
PRB4
PRH1
PTH
PTN
RCN1
RELL2
RNASEH1
SCGB1C2
SDC2
SF3A2
SGTB
SHISAL1
SLC51B
SMIM11A
SMIM11B
SMIM19
SOD3
SPINK1
TMEM167B
TMX2
TNFRSF10B
TRDN
TUFM
TXNDC15
UGT2B11
WFDC12
WFDC5
ZG16
8 interacting genes:
AQP6
ASPH
GPR37L1
MTIF3
PPIB
TAC3
TMCO5A
TMEM14B
Entrez ID
444
5554
HPRD ID
08996
01349
Ensembl ID
ENSG00000198363
ENSG00000231887
Uniprot IDs
B4DQ07
B7ZM96
Q12797
A0A087WV42
F1T0A8
P02810
PDB IDs
5APA
5JQY
5JTC
5JZ6
5JZ8
5JZA
5JZU
6Q9F
6Q9I
6QA5
6RK9
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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