ASPH and RELL2

Data Source:
BioGRID (two hybrid)

		ASPH	RELL2
Description		aspartate beta-hydroxylase	RELT like 2
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Cortical Endoplasmic Reticulum Sarcoplasmic Reticulum Membrane	Basement Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	Peptide-aspartate Beta-dioxygenase Activity Structural Molecule Activity Calcium Ion Binding Protein Binding Structural Constituent Of Muscle Electron Transfer Activity Peptidyl-aspartic Acid 3-dioxygenase Activity	Protein Binding Collagen Binding
	Biological Process	Muscle Contraction Protein Phosphopantetheinylation Electron Transport Chain Ion Transmembrane Transport Peptidyl-aspartic Acid Hydroxylation Positive Regulation Of Proteolysis Activation Of Cysteine-type Endopeptidase Activity Regulation Of Cardiac Conduction	Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of P38MAPK Cascade
Pathways		Stimuli-sensing channels Ion homeostasis
Drugs		Aspartic acid
Diseases
GWAS		Blood protein levels ( 30072576 29875488) BRCA1/2-negative high-risk breast cancer ( 30323354) Resting heart rate ( 28270201) Serum omega-6 to omega-3 polyunsaturated fatty acid ratio in metabolic syndrome ( 31991592) Urate levels in overweight individuals ( 25811787)	Refractive error ( 32231278)
Interacting Genes		71 interacting genes: AGR2 APP BGLAP CDSN CHRM5 CST1 CTSA CXorf66 DCD DEFB1 DHRSX ENPP6 FBXO7 FDCSP FGFBP1 FKBP7 GAL GAST GET3 GOLM1 GPR119 GPX7 GPX8 GSC2 GUCA2A IL21 INSL5 KCNIP1 KCNIP3 KCNIP4 LCN2 LRPAP1 LTA NUCB2 OCIAD1 PCSK4 PDGFA PDGFRL PLAAT2 PLEKHF2 PRAP1 PRB1 PRB2 PRB4 PRH1 PTH PTN RCN1 RELL2 RNASEH1 SCGB1C2 SDC2 SF3A2 SGTB SHISAL1 SLC51B SMIM11A SMIM11B SMIM19 SOD3 SPINK1 TMEM167B TMX2 TNFRSF10B TRDN TUFM TXNDC15 UGT2B11 WFDC12 WFDC5 ZG16	21 interacting genes: ANKRD46 ASPH CDIPT CLDND2 COL4A5 FAM3C LPAR3 MIP NSG1 OXSR1 PLP1 RELL1 RTP2 SEC22B SLC30A8 SLC35A1 SMIM1 TFRC TSPAN33 TSPO2 ZFPL1
Entrez ID		444	285613
HPRD ID		08996	12830
Ensembl ID		ENSG00000198363	ENSG00000164620
Uniprot IDs		B4DQ07 B7ZM96 Q12797	Q8NC24
PDB IDs		5APA 5JQY 5JTC 5JZ6 5JZ8 5JZA 5JZU 6Q9F 6Q9I 6QA5 6RK9
Enriched GO Terms of Interacting Partners?
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