NRARP and GTF2E1

Data Source:
BioGRID (two hybrid)

		NRARP	GTF2E1
Description		NOTCH regulated ankyrin repeat protein	general transcription factor IIE subunit 1
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GO Annotations	Cellular Component		Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIE Complex Cytosol Transcription Preinitiation Complex
	Molecular Function	Protein Binding	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Branching Involved In Blood Vessel Morphogenesis Positive Regulation Of Endothelial Cell Proliferation Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis Notch Signaling Pathway Somite Rostral/caudal Axis Specification Negative Regulation Of T Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Notch Signaling Pathway Involved In Somitogenesis	Transcription Open Complex Formation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Macular thickness ( 30535121)	Obesity-related traits ( 23251661)
Interacting Genes		2 interacting genes: GTF2E1 IKBKG	34 interacting genes: APP CBFA2T2 CDK7 ERCC2 ERCC3 GTF2A1 GTF2A2 GTF2B GTF2E2 GTF2F1 GTF2F2 GTF2H1 GTF2H2 GTF2H3 GTF2H4 GTF2H5 IKBKG NRARP PCBD2 POLR2A SND1 SRPK2 TAF1 TAF11 TAF6 TBC1D21 TBP TCEA1 TLE5 TRIM15 TRIM24 TRIM29 ZBTB9 ZSCAN1
Entrez ID		441478	2960
HPRD ID		17564	01799
Ensembl ID		ENSG00000198435	ENSG00000153767
Uniprot IDs		Q7Z6K4	P29083
PDB IDs		6PY8	1VD4 2JTX 2RNQ 2RNR 5GPY 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 6O9L
Enriched GO Terms of Interacting Partners?
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