KRTAP5-11 and SPRY4

Data Source:
BioGRID (two hybrid)

		KRTAP5-11	SPRY4
Description		keratin associated protein 5-11	sprouty RTK signaling antagonist 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Cytoplasm Cytosol Focal Adhesion Ruffle Membrane
	Molecular Function	Protein Binding	Protein Kinase Inhibitor Activity Protein Binding
	Biological Process	Keratinization	Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Negative Regulation Of MAP Kinase Activity Negative Regulation Of Ras Protein Signal Transduction Animal Organ Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Keratinization
Drugs
Diseases
GWAS			Asthma ( 31959851 29273806) Body mass index ( 28552196) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Gut microbiota (bacterial taxa) ( 27723756) Height ( 31562340) Inflammatory bowel disease ( 23128233) Physiological traits ( 31902109) Systolic blood pressure ( 30578418) Testicular germ cell cancer ( 20543847) Testicular germ cell tumor ( 19483681 28604728 28604732 23666239 23666240)
Interacting Genes		58 interacting genes: CATSPER1 CRCT1 CREB5 CYSRT1 FAM76B GLRX3 GORASP2 HOXA1 KRTAP1-1 KRTAP1-3 KRTAP1-5 KRTAP10-6 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP13-3 KRTAP15-1 KRTAP17-1 KRTAP2-3 KRTAP2-4 KRTAP4-4 KRTAP5-7 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-8 LCE1A LCE1B LCE1C LCE1D LCE1E LCE1F LCE2C LCE3A LCE3B LCE3C LCE3E LCE4A LCE5A LELP1 MEOX2 NBPF19 NECTIN3 NOTCH2NLA NR4A3 NUFIP2 OTX1 POU4F2 RGS17 RGS20 SH3GLB2 SMCP SPRY4 TMEM190 TRIM42 VASN VGLL3	17 interacting genes: ADAM12 COL8A1 CREB5 EFEMP2 FHL2 HOXA1 KLHL38 KRTAP5-11 NUTF2 OTX1 POU4F2 RAF1 RIN3 TESK1 TNS2 VENTX ZDHHC17
Entrez ID		440051	81848
HPRD ID		17248	10466
Ensembl ID		ENSG00000204571	ENSG00000187678
Uniprot IDs		Q6L8G4	A0A0C4DFS6 Q9C004
PDB IDs			3BUN
Enriched GO Terms of Interacting Partners?
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