MMP10 and BCAN

Data Source:
HPRD (in vitro)

		MMP10	BCAN
Description		matrix metallopeptidase 10	brevican
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix	Extracellular Region Golgi Lumen Extracellular Matrix Anchored Component Of Membrane Lysosomal Lumen Glutamatergic Synapse
	Molecular Function	Metalloendopeptidase Activity Zinc Ion Binding	Protein Binding Hyaluronic Acid Binding Carbohydrate Binding
	Biological Process	Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process	Skeletal System Development Cell Adhesion Central Nervous System Development Hippocampus Development Extracellular Matrix Organization Chondroitin Sulfate Biosynthetic Process Chondroitin Sulfate Catabolic Process Dermatan Sulfate Biosynthetic Process Synapse Maturation
Pathways		Collagen degradation Collagen degradation Degradation of the extracellular matrix Degradation of the extracellular matrix Activation of Matrix Metalloproteinases	Degradation of the extracellular matrix A tetrasaccharide linker sequence is required for GAG synthesis Chondroitin sulfate biosynthesis Dermatan sulfate biosynthesis CS/DS degradation ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective CHST14 causes EDS, musculocontractural type Defective CHSY1 causes TPBS Defective B3GALT6 causes EDSP2 and SEMDJL1
Drugs		Marimastat N-ISOBUTYL-N-[4-METHOXYPHENYLSULFONYL]GLYCYL HYDROXAMIC ACID
Diseases
GWAS		Blood protein levels ( 30072576 29875488) Multiple sclerosis ( 23412934) Prostate cancer ( 23535732)	Blood protein levels ( 30072576 29875488)
Interacting Genes		3 interacting genes: BCAN HAPLN1 MMP9	10 interacting genes: ADAMTS4 FBLN2 MMP1 MMP10 MMP13 MMP2 MMP3 MMP7 MMP8 TNR
Entrez ID		4319	63827
HPRD ID		01704	02644
Ensembl ID		ENSG00000166670	ENSG00000132692
Uniprot IDs		P09238	Q96GW7
PDB IDs		1Q3A 3V96 4ILW
Enriched GO Terms of Interacting Partners?
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