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MGST2 and SEC22B
Data Source:
BioGRID
(two hybrid)
MGST2
SEC22B
Description
microsomal glutathione S-transferase 2
SEC22 homolog B, vesicle trafficking protein
Image
No pdb structure
GO Annotations
Cellular Component
Nuclear Envelope
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Plasma Membrane
Membrane
Integral Component Of Membrane
Intracellular Membrane-bounded Organelle
Golgi Membrane
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Synaptic Vesicle
ER To Golgi Transport Vesicle Membrane
Integral Component Of Membrane
Transport Vesicle
COPI-coated Vesicle
Phagocytic Vesicle Membrane
SNARE Complex
Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
Melanosome
Molecular Function
Glutathione Transferase Activity
Leukotriene-C4 Synthase Activity
Glutathione Peroxidase Activity
Protein Binding
Enzyme Activator Activity
Identical Protein Binding
Glutathione Binding
SNAP Receptor Activity
Protein Binding
Syntaxin Binding
Biological Process
Lipid Metabolic Process
Glutathione Biosynthetic Process
Xenobiotic Metabolic Process
Response To Organonitrogen Compound
Leukotriene Biosynthetic Process
Response To Lipopolysaccharide
Membrane Lipid Catabolic Process
Positive Regulation Of Inflammatory Response
Regulation Of Catalytic Activity
Cellular Oxidant Detoxification
Glutathione Derivative Biosynthetic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Endoplasmic Reticulum To Golgi Vesicle-mediated Transport
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Protein Transport
Positive Regulation Of Protein Catabolic Process
COPII Vesicle Coating
Vesicle Fusion With Golgi Apparatus
Negative Regulation Of Autophagosome Assembly
Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane
Pathways
Glutathione conjugation
Aflatoxin activation and detoxification
ER-Phagosome pathway
COPII-mediated vesicle transport
Cargo concentration in the ER
COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Glutathione
Diseases
GWAS
Metabolite levels (
23823483
)
Iris color (L* coordinate) (
30895295
)
Interacting Genes
23 interacting genes:
ASIC1
BCL2L10
BCL2L2
C3orf52
CCL3L3
CLEC14A
CREB3
CREB3L1
CTXN3
DNAJC30
GIMAP5
GJA8
GPX8
HDHD2
PLN
PNKP
SEC22A
SEC22B
SGCB
STX8
TMEM167B
TMEM207
VAMP3
56 interacting genes:
ABHD16A
AIG1
AQP6
B3GAT3
CD79A
CERS6
CLDN7
CLRN1
CPLX4
CREB3
CREB3L1
DPM3
EBP
ELOVL4
ERGIC3
FAM174A
FAM209A
FCER1G
FNDC9
GJA8
GJB5
GJB6
GORAB
GPR152
GPX8
HIBADH
HSD17B11
HSD17B13
IFNGR2
JAGN1
KIR2DL3
LHFPL1
LHFPL5
LMNA
MFF
MFSD5
MGST2
MGST3
MMGT1
MRPS18B
NDUFAF2
REEP4
RELL2
RHBDD1
SERINC2
SLC35C2
STX1A
STX2
STX4
STX5
TLCD4
TM4SF19
TMEM139
TMEM167B
TMEM229B
TMEM86B
Entrez ID
4258
9554
HPRD ID
03436
04939
Ensembl ID
ENSG00000085871
ENSG00000265808
Uniprot IDs
Q99735
O75396
PDB IDs
2NUP
2NUT
3EGD
3EGX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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