MGST2 and BCL2L10

Data Source:
BioGRID (two hybrid)

		MGST2	BCL2L10
Description		microsomal glutathione S-transferase 2	BCL2 like 10
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Cytosol Membrane Integral Component Of Membrane Nuclear Membrane Mitochondria-associated Endoplasmic Reticulum Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Identical Protein Binding Glutathione Binding	Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Caspase Binding
	Biological Process	Lipid Metabolic Process Glutathione Biosynthetic Process Xenobiotic Metabolic Process Response To Organonitrogen Compound Leukotriene Biosynthetic Process Response To Lipopolysaccharide Membrane Lipid Catabolic Process Positive Regulation Of Inflammatory Response Regulation Of Catalytic Activity Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Spermatogenesis Female Gamete Generation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Apoptotic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Glutathione conjugation Aflatoxin activation and detoxification
Drugs		Glutathione
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		23 interacting genes: ASIC1 BCL2L10 BCL2L2 C3orf52 CCL3L3 CLEC14A CREB3 CREB3L1 CTXN3 DNAJC30 GIMAP5 GJA8 GPX8 HDHD2 PLN PNKP SEC22A SEC22B SGCB STX8 TMEM167B TMEM207 VAMP3	15 interacting genes: APAF1 BAD BAK1 BAX BCL2 BCL2L1 BCL2L11 BECN1 BIK BMF CASP8 MGST2 NR4A1 SAMD4B TMEM200A
Entrez ID		4258	10017
HPRD ID		03436	06071
Ensembl ID		ENSG00000085871	ENSG00000137875
Uniprot IDs		Q99735	H0YMD5 Q9HD36
PDB IDs			4B4S
Enriched GO Terms of Interacting Partners?
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