MGST1 and FXYD3

Data Source:
BioGRID (two hybrid)

		MGST1	FXYD3
Description		microsomal glutathione S-transferase 1	FXYD domain containing ion transport regulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Outer Membrane Peroxisomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Azurophil Granule Membrane Apical Part Of Cell	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Protein Binding Identical Protein Binding Glutathione Binding	Chloride Channel Activity Sodium Channel Regulator Activity Ion Channel Regulator Activity
	Biological Process	Xenobiotic Metabolic Process Response To Organonitrogen Compound Response To Lipopolysaccharide Leydig Cell Differentiation Response To Drug Neutrophil Degranulation Cellular Response To Lipid Hydroperoxide Cellular Oxidant Detoxification Glutathione Derivative Biosynthetic Process	Potassium Ion Transport Sodium Ion Transport Chloride Transport Ion Transmembrane Transport Chloride Transmembrane Transport Regulation Of Cardiac Conduction Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways		Glutathione conjugation Aflatoxin activation and detoxification Neutrophil degranulation	Ion homeostasis Ion transport by P-type ATPases Potential therapeutics for SARS
Drugs		Glutathione Glutathione disulfide
Diseases
GWAS		Colorectal cancer (aspirin and/or NSAID use interaction) ( 25781442) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Visceral fat ( 22589738)
Interacting Genes		8 interacting genes: EGF FXYD3 FZD7 LTC4S NELFB SIGLEC12 TNFRSF10C VIP	64 interacting genes: AGR3 ANK1 AQP6 AQP9 BCL2L13 BEST2 CD79A CNR2 CREB3 CREB3L1 CYB5R3 EBP ERG28 ERGIC3 FAM209A FBXL12 FCGR2A FFAR2 GHITM GPR152 GPR37L1 GPR42 GPRC5D IBSP KASH5 KCNN4 LMNA LTC4S MAPK6 MFSD11 MFSD5 MGST1 MTIF3 NR4A1 NUDT3 PLPP6 SCN3B SERBP1 SGPL1 SLC10A1 SLC10A6 SLC16A12 SLC18A1 SLC1A1 SLC30A2 SLC35A1 SLC35B1 SLC35C2 SLC39A2 SPNS3 STRIT1 STX3 TIMM23 TIMMDC1 TLCD1 TMBIM6 TMEM179B TMEM50B TMEM52B TMEM80 TMEM86A TMEM97 TSPO2 XKR3
Entrez ID		4257	5349
HPRD ID		00705	05410
Ensembl ID		ENSG00000008394	ENSG00000089356
Uniprot IDs		A0A024RAX2 P10620	Q14802
PDB IDs
Enriched GO Terms of Interacting Partners?
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