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MARS1 and MIR140
Data Source:
BioGRID
(unspecified method)
MARS1
MIR140
Description
methionyl-tRNA synthetase 1
microRNA 140
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Cytoplasm
Cytosol
Membrane
Aminoacyl-tRNA Synthetase Multienzyme Complex
Extracellular Exosome
Extracellular Space
Molecular Function
TRNA Binding
Methionine-tRNA Ligase Activity
ATP Binding
RNA Polymerase II Complex Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
TRNA Aminoacylation For Protein Translation
Methionyl-tRNA Aminoacylation
Cellular Response To Starvation
RRNA Transcription
Cellular Response To Insulin Stimulus
Cellular Response To Platelet-derived Growth Factor Stimulus
Cellular Response To Epidermal Growth Factor Stimulus
Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I
Positive Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Positive Regulation Of BMP Signaling Pathway
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Tumor Necrosis Factor Production
Negative Regulation Of Toll-like Receptor 4 Signaling Pathway
Gene Silencing By MiRNA
Defense Response To Bacterium
Cellular Response To Lipopolysaccharide
Cellular Response To Hypoxia
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Negative Regulation Of Vascular Endothelial Growth Factor Production
Cellular Response To Amyloid-beta
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Vascular Associated Smooth Muscle Cell Differentiation Involved In Phenotypic Switching
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS
Body mass index (
26426971
)
Interacting Genes
79 interacting genes:
CASK
DUX4
ESR1
HNRNPUL1
MAFK
MAPK14
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
PPM1F
RPS27
SUMO2
TNNT1
68 interacting genes:
ADARB1
AIMP1
APOBEC3B
C1QBP
CELF1
CELF2
CRTAP
CSTF1
DARS1
DDX1
DDX21
DDX3X
DDX49
EIF2AK2
EPRS1
FAM98A
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LIN28A
LRPPRC
MARS1
MATR3
NOL6
NONO
NUDT21
PDCD11
PIKFYVE
PIP5K1A
PTBP1
PTBP3
PUF60
PUM1
PURA
QARS1
RARS1
RBFOX2
RBM14
RTCB
SF3B1
SF3B3
SFPQ
SYNCRIP
TAF15
TRA2A
TRA2B
UPF1
UTP20
YBX1
YBX3
Entrez ID
4141
406932
HPRD ID
08864
Ensembl ID
ENSG00000166986
ENSG00000208017
Uniprot IDs
P56192
PDB IDs
2DJV
4BL7
4BVX
4BVY
5GL7
5GOY
5Y6L
Enriched GO Terms of Interacting Partners
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