MARS1 and MIR138-1

Data Source:
BioGRID (unspecified method)

		MARS1	MIR138-1
Description		methionyl-tRNA synthetase 1	microRNA 138-1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleolus Cytoplasm Cytosol Membrane Aminoacyl-tRNA Synthetase Multienzyme Complex Extracellular Exosome	Nucleus Cytoplasm
	Molecular Function	TRNA Binding Methionine-tRNA Ligase Activity ATP Binding	MRNA Binding Involved In Posttranscriptional Gene Silencing
	Biological Process	TRNA Aminoacylation For Protein Translation Methionyl-tRNA Aminoacylation Cellular Response To Starvation RRNA Transcription Cellular Response To Insulin Stimulus Cellular Response To Platelet-derived Growth Factor Stimulus Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of Transcription Of Nucleolar Large RRNA By RNA Polymerase I	Negative Regulation Of Cell Adhesion Negative Regulation Of Cell Population Proliferation Negative Regulation Of Gene Expression Negative Regulation Of Cell Migration Negative Regulation Of NF-kappaB Transcription Factor Activity Negative Regulation Of Osteoblast Proliferation Gene Silencing By MiRNA MiRNA Mediated Inhibition Of Translation Negative Regulation Of Phosphatidylinositol 3-kinase Activity Plasma Membrane Raft Assembly Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Inflammatory Response Negative Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Stress Fiber Assembly Positive Regulation Of Protein Kinase B Signaling Negative Regulation Of Response To Cytokine Stimulus Negative Regulation Of Protein K63-linked Ubiquitination Negative Regulation Of Sprouting Angiogenesis Negative Regulation Of P38MAPK Cascade Negative Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		Selenoamino acid metabolism Cytosolic tRNA aminoacylation
Drugs
Diseases
GWAS			Schizophrenia ( 30285260)
Interacting Genes		79 interacting genes: CASK DUX4 ESR1 HNRNPUL1 MAFK MAPK14 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I PPM1F RPS27 SUMO2 TNNT1	67 interacting genes: ADARB1 C1QBP CPSF1 DARS1 DDX1 DDX21 DDX3X DHX36 EIF2AK2 EPRS1 ERAL1 ESRP1 FAM98A FAM98B FUS HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 LARP7 LIN28A LRPPRC MARS1 MATR3 NONO NUDT16L1 NUDT21 PDCD11 PRMT1 PTBP1 PTBP3 PUM1 QARS1 RARS1 RBM14 RBM4 RTCB SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SPOUT1 STRBP SYNCRIP TAF15 TENT2 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX3
Entrez ID		4141	406929
HPRD ID		08864
Ensembl ID		ENSG00000166986	ENSG00000207954
Uniprot IDs		P56192
PDB IDs		2DJV 4BL7 4BVX 4BVY 5GL7 5GOY 5Y6L
Enriched GO Terms of Interacting Partners?
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