MARK1 and YAF2

Data Source:
BioGRID (two hybrid)

		MARK1	YAF2
Description		microtubule affinity regulating kinase 1	YY1 associated factor 2
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Dendrite	Nucleus Nucleoplasm Cytosol
	Molecular Function	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau Protein Binding Tau-protein Kinase Activity Phosphatidic Acid Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Protein Phosphorylation Cytoskeleton Organization Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Dendrite Development Establishment Of Mitochondrion Localization	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs		Fostamatinib
Diseases
GWAS		Bipolar disorder ( 22205951) Breast size ( 27182965) Fat distribution (HIV) ( 21897333)	Refractive error ( 32231278)
Interacting Genes		10 interacting genes: CCDC102B GJA5 INCA1 MAP2 MAP4 MAPT STK11 TAOK1 TCL1B YAF2	29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42
Entrez ID		4139	10138
HPRD ID		07353	09606
Ensembl ID		ENSG00000116141	ENSG00000015153
Uniprot IDs		A0A087X0I6 B4DIB3 Q9P0L2 X5D2M4	B4DJQ9 G3V212 Q8IY57
PDB IDs		2HAK 3OSE 6C9D	2D9G
Enriched GO Terms of Interacting Partners?
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