YAF2 and PCDH17

Data Source:
BioGRID (two hybrid)

		YAF2	PCDH17
Description		YY1 associated factor 2	protocadherin 17
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Integral Component Of Plasma Membrane Glutamatergic Synapse GABA-ergic Synapse Integral Component Of Postsynaptic Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Adult Behavior Negative Regulation Of Synaptic Transmission Synaptic Membrane Adhesion Presynaptic Active Zone Assembly Regulation Of Synaptic Vesicle Clustering
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Transcriptional Regulation by E2F6
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Adult body size ( 32376654) Body mass index ( 25673413) Body size at age 10 ( 32376654) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Cognitive function ( 25644384) Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Experiencing mood swings ( 29500382) Fish- and plant-related diet ( 32066663) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mood instability ( 31168069) Neonatal total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) Oily fish consumption ( 32066663) Pork consumption ( 32066663) Regular attendance at a religious group ( 29970889) Subcutaneous adipose tissue ( 26480920 22589738) Type 2 diabetes ( 30297969)
Interacting Genes		29 interacting genes: ANP32B CAVIN1 CD300LF DNAAF6 EAF1 GABPB1 IFT57 INO80B LGALS7 LGALS7B MAPRE3 MARK1 MYC MYCN NEDD8 NUTF2 PCDH17 POLR3GL PPP1R11 RING1 RNF2 SETBP1 SPANXN2 SPANXN3 TLK1 UBC XAGE1B YY1 ZFP42	5 interacting genes: NR1H2 TSC22D4 UBQLN4 YAF2 ZP3
Entrez ID		10138	27253
HPRD ID		09606	15104
Ensembl ID		ENSG00000015153	ENSG00000118946
Uniprot IDs		B4DJQ9 G3V212 Q8IY57	O14917
PDB IDs		2D9G	6VFT
Enriched GO Terms of Interacting Partners?
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