MARK1 and TCL1B

Data Source:
BioGRID (two hybrid)

		MARK1	TCL1B
Description		microtubule affinity regulating kinase 1	TCL1 family AKT coactivator B
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton Dendrite	Protein-containing Complex
	Molecular Function	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau Protein Binding Tau-protein Kinase Activity Phosphatidic Acid Binding Protein Serine Kinase Activity Protein Threonine Kinase Activity	Protein Binding Protein Kinase Binding Protein Serine/threonine Kinase Activator Activity
	Biological Process	Microtubule Cytoskeleton Organization Neuron Migration Protein Phosphorylation Cytoskeleton Organization Regulation Of Neuron Projection Development Wnt Signaling Pathway Peptidyl-serine Phosphorylation Intracellular Signal Transduction Regulation Of Dendrite Development Establishment Of Mitochondrion Localization	Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs		Fostamatinib
Diseases
GWAS		Bipolar disorder ( 22205951) Breast size ( 27182965) Fat distribution (HIV) ( 21897333)	Refractive error ( 32231278)
Interacting Genes		10 interacting genes: CCDC102B GJA5 INCA1 MAP2 MAP4 MAPT STK11 TAOK1 TCL1B YAF2	17 interacting genes: AKT1 AKT2 APP BAG4 EFCAB2 GLRX3 LSM1 LSM5 LSM7 MARK1 MEIS3 MKRN3 PLEKHA3 PNMA1 SNRPG TNPO2 ZNF330
Entrez ID		4139	9623
HPRD ID		07353	04795
Ensembl ID		ENSG00000116141	ENSG00000213231
Uniprot IDs		A0A087X0I6 B4DIB3 Q9P0L2 X5D2M4	A0A024R6P4 O95988
PDB IDs		2HAK 3OSE 6C9D
Enriched GO Terms of Interacting Partners?
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