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LARS1 and MIR106A
Data Source:
BioGRID
(unspecified method)
LARS1
MIR106A
Description
leucyl-tRNA synthetase 1
microRNA 106a
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Lysosome
Endoplasmic Reticulum
Cytosol
Endomembrane System
Nuclear Body
Aminoacyl-tRNA Synthetase Multienzyme Complex
Extracellular Space
Extracellular Vesicle
Molecular Function
Aminoacyl-tRNA Editing Activity
Glutamine-tRNA Ligase Activity
Leucine-tRNA Ligase Activity
GTPase Activator Activity
Protein Binding
ATP Binding
MRNA 3'-UTR Binding
MRNA Binding Involved In Posttranscriptional Gene Silencing
Biological Process
TRNA Aminoacylation For Protein Translation
Glutaminyl-tRNA Aminoacylation
Leucyl-tRNA Aminoacylation
Regulation Of Cell Size
Positive Regulation Of TOR Signaling
Cellular Response To Amino Acid Starvation
Positive Regulation Of GTPase Activity
Cellular Response To Amino Acid Stimulus
Cellular Response To Leucine
Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Positive Regulation Of TORC1 Signaling
Cellular Response To Leucine Starvation
Negative Regulation Of Interleukin-10 Production
Negative Regulation Of Interleukin-8 Production
Gene Silencing By MiRNA
MiRNA Mediated Inhibition Of Translation
Negative Regulation Of Amyloid Precursor Protein Biosynthetic Process
Negative Regulation Of Vascular Endothelial Growth Factor Production
Pathways
Selenoamino acid metabolism
Cytosolic tRNA aminoacylation
Drugs
Leucine
Diseases
GWAS
Interacting Genes
55 interacting genes:
CDC42
EEF1G
ESR1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR128-1
MIR128-2
MIR138-2
MIR15A
MIR15B
MIR17
MIR18A
MIR18B
MIR199A1
MIR19B1
MIR19B2
MIR200A
MIR205
MIR206
MIR20B
MIR21
MIR214
MIR221
MIR25
MIR29A
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR451A
MIR7-1
MIR7-2
MIR9-1
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
SUMO2
82 interacting genes:
ADARB1
AIMP2
APOBEC3B
AQR
C1QBP
DARS1
DDX1
DDX21
DDX3X
DDX3Y
DHX36
EDC4
EIF2AK2
EPRS1
ERAL1
ESRP1
FAM98A
FAM98B
FUS
G3BP2
HNRNPA0
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPF
HNRNPH1
HNRNPH2
HNRNPH3
HNRNPK
HNRNPL
HNRNPM
HNRNPR
IARS1
IGF2BP1
IGF2BP2
IGF2BP3
KARS1
KNOP1
LARP7
LARS1
LIN28A
LIN28B
LRPPRC
MARS1
MATR3
MSI2
NONO
NUDT21
PDCD11
PGAM5
PRMT1
PTBP1
PTBP3
PUF60
PUM1
QARS1
RARS1
RBFOX2
RBM14
RBM4
RTCB
SF3A1
SF3B1
SF3B2
SF3B3
SF3B4
SFPQ
SPOUT1
STRBP
SUGP2
SYNCRIP
TAF15
TIAL1
TRA2B
TRMT1L
U2SURP
UPF1
UTP20
YBX1
YBX3
ZFR
ZNF346
Entrez ID
51520
406899
HPRD ID
01042
Ensembl ID
ENSG00000133706
ENSG00000284157
Uniprot IDs
A0A6I8PL42
B4DER1
B4E266
Q9P2J5
PDB IDs
2WFD
6LPF
6LR6
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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