LY9 and SH2D1B

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		LY9	SH2D1B
Description		lymphocyte antigen 9	SH2 domain containing 1B
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Cytosol
	Molecular Function	Molecular_function	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Cell Adhesion Positive Regulation Of Interleukin-17 Production Innate Immune Response T-helper 17 Cell Lineage Commitment	Adaptive Immune Response Leukocyte Activation Involved In Immune Response Positive Regulation Of Natural Killer Cell Mediated Immunity Innate Immune Response Positive Regulation Of Innate Immune Response Regulation Of Immune Response
Pathways			Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases
GWAS		Blood protein levels ( 29875488 28240269) Lymphocyte counts ( 32888494 27863252) Lymphocyte percentage of white cells ( 32888494 27863252) Monocyte count ( 32888494) White blood cell count ( 32888494)	Sum of carotid plaque area ( 32469969) Sum of stenosis ( 32469969) Takayasu arteritis ( 25604533)
Interacting Genes		3 interacting genes: AP2M1 SH2D1A SH2D1B	25 interacting genes: AGR2 APP AR BLK CD244 CD84 EGFR ERBB2 ERBB3 ERBB4 GAB1 KIT LY9 MAGEB4 MAPK8IP2 MEOX2 MET NFKBID NUTM1 PRDX1 PTK2 SLAMF1 STAT4 TNK2 TRIM54
Entrez ID		4063	117157
HPRD ID		02817	12248
Ensembl ID		ENSG00000122224	ENSG00000198574
Uniprot IDs		A0A0C4DFU4 Q05CA2 Q0VAI0 Q5VYH9 Q9HBG7	O14796
PDB IDs			5KAZ
Enriched GO Terms of Interacting Partners?
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