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ARNT and GTF2F2
Data Source:
HPRD
(in vitro)
ARNT
GTF2F2
Description
aryl hydrocarbon receptor nuclear translocator
general transcription factor IIF subunit 2
Image
GO Annotations
Cellular Component
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Aryl Hydrocarbon Receptor Complex
RNA Polymerase II Transcription Regulator Complex
Nucleus
Nucleoplasm
Transcription Factor TFIIF Complex
Microtubule Cytoskeleton
Transcription Preinitiation Complex
Molecular Function
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity
Nuclear Receptor Activity
Protein Binding
Transcription Factor Binding
Aryl Hydrocarbon Receptor Binding
Protein Homodimerization Activity
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Sequence-specific Double-stranded DNA Binding
DNA Binding
DNA Helicase Activity
Protein Binding
ATP Binding
RNA Polymerase II General Transcription Initiation Factor Activity
Biological Process
Response To Hypoxia
Embryonic Placenta Development
Positive Regulation Of Endothelial Cell Proliferation
Regulation Of Transcription By RNA Polymerase II
Xenobiotic Metabolic Process
Positive Regulation Of Vascular Endothelial Growth Factor Production
Cell Differentiation
Intracellular Receptor Signaling Pathway
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Sumoylation
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Glycolytic Process
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Hormone Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
MRNA Splicing, Via Spliceosome
Transcription By RNA Polymerase II
Transcription Initiation From RNA Polymerase II Promoter
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Fibroblast Growth Factor Receptor Signaling Pathway
RNA Metabolic Process
DNA Duplex Unwinding
SnRNA Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Pathways
Regulation of gene expression by Hypoxia-inducible Factor
PPARA activates gene expression
Phase I - Functionalization of compounds
Endogenous sterols
Xenobiotics
Aryl hydrocarbon receptor signalling
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Drugs
Diseases
GWAS
Blood protein levels (
28240269
)
Body mass index (
26426971
)
Congenital left-sided heart lesions (
26965164
)
Cutaneous squamous cell carcinoma (
32041948
)
Estimated glomerular filtration rate (
31451708
)
Estimated glomerular filtration rate in non-diabetics (
31451708
)
Melanoma (
21983785
28212542
)
Metabolic syndrome (
31589552
)
Platelet count (
32888494
)
Rhegmatogenous retinal detachment (
23585552
)
Tea consumption (
31046077
)
Urate levels (
23263486
)
Normal facial asymmetry (angle of surface orientation score) (
30631343
)
Type 2 diabetes (
25760438
)
Interacting Genes
77 interacting genes:
ADH5
AHR
AHRR
AIP
AKT1
ARL14
ARNT2
BECN1
BRCA1
CALCOCO1
CASP3
CASP9
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CDKN2C
CSNK2A1
DIABLO
EP300
EPAS1
EPHA2
ERBB2
ESR1
FGFR4
FZR1
GLIS1
GLIS2
GMNN
GTF2F1
GTF2F2
HEY1
HEY2
HGF
HIF1A
HIF3A
HNF4A
IRAK4
KPNA1
KPNA3
KPNA5
KPNA6
LATS2
LSM8
MAP2K5
MAPK14
MTA3
MYC
NCOA1
NCOA2
NCOA7
NCOR2
NF2
NPAS4
PDGFRA
PML
PTGES3
RAF1
RELA
SENP6
SIM1
SIM2
SMAD9
SP1
STK11
STRBP
TACC3
TEAD2
TGM2
TNFAIP1
TP53
TRIP11
TUBB2A
UBE2I
30 interacting genes:
AHR
AR
ARNT
ATF2
ATF4
CEBPG
CREB1
DYNLT2B
FHL2
FOS
GTF2B
GTF2E1
GTF2E2
GTF2F1
HMGA1
HTATSF1
JUN
KLF5
MAPRE3
MSX2
MYC
POLR2E
RPL27A
TAF5
TBP
TCEA1
TRAM2
URI1
YEATS4
ZMYND19
Entrez ID
405
2963
HPRD ID
00524
01804
Ensembl ID
ENSG00000143437
ENSG00000188342
Uniprot IDs
A8K6P0
B0AZM1
P27540
Q53F30
A0A024RDU9
P13984
PDB IDs
1D7G
1X0O
2A24
2ARN
2B02
2HV1
2K7S
3F1N
3F1O
3F1P
3H7W
3H82
4EQ1
4GHI
4GS9
4H6J
4LPZ
4PKY
4XT2
5TBM
5UFP
5V0L
6CZW
6D09
6D0B
6D0C
1BBY
1F3U
2BBY
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
6O9L
Enriched GO Terms of Interacting Partners
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