VWA5A and RDX

Data Source:
BioGRID (affinity chromatography technology)

		VWA5A	RDX
Description		von Willebrand factor A domain containing 5A	radixin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm	Extracellular Space Plasma Membrane Microvillus Adherens Junction Focal Adhesion Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Cell Tip Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding	RNA Binding Actin Binding Protein Binding Cadherin Binding Protein Kinase A Binding ATPase Binding
	Biological Process		Regulation Of Cell Shape Regulation Of Cell Size Positive Regulation Of Gene Expression Protein Kinase A Signaling Positive Regulation Of Cell Migration Regulation Of Actin Filament Bundle Assembly Regulation Of Rap Protein Signal Transduction Negative Regulation Of Homotypic Cell-cell Adhesion Negative Regulation Of GTPase Activity Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of GTPase Activity Apical Protein Localization Establishment Of Protein Localization Negative Regulation Of Cell Size Barbed-end Actin Filament Capping Establishment Of Endothelial Barrier Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Ruffle Assembly Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways			Recycling pathway of L1 Recycling pathway of L1
Drugs			1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Aging (time to death) ( 21782286)	Cognitive function ( 24684796) Coronary artery disease ( 32469254) Multiple sclerosis ( 31604244)
Interacting Genes		6 interacting genes: APP MEOX2 PPARA PRTFDC1 RHOU SPSB1	20 interacting genes: ABCC2 ARHGDIA C1QTNF9 CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 L1CAM LINC01554 PSME3 ROCK1 SLC9A3R1 SLC9A3R2 TSC1 VPS11
Entrez ID		4013	5962
HPRD ID		04238	01534
Ensembl ID		ENSG00000110002	ENSG00000137710
Uniprot IDs		A0A024R3H3 O00534	B0YJ88 P35241 Q6PKD3
PDB IDs
Enriched GO Terms of Interacting Partners?
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