LNPEP and SLC35E3

Data Source:
BioGRID (two hybrid)

		LNPEP	SLC35E3
Description		leucyl and cystinyl aminopeptidase	solute carrier family 35 member E3
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Lumen	Golgi Apparatus Integral Component Of Membrane
	Molecular Function	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Nucleotide-sugar Transmembrane Transporter Activity Protein Binding Antiporter Activity
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Signal Transduction Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Peptide Catabolic Process Negative Regulation Of Cold-induced Thermogenesis	Nucleobase-containing Compound Transport Transmembrane Transport Carbohydrate Derivative Transport
Pathways		Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)	Mean reticulocyte volume ( 32888494) White blood cell count ( 20139978)
Interacting Genes		33 interacting genes: AGT AQP6 ASGR2 CGRRF1 CTAG1A CTAG1B FAM210B FATE1 FCER1G FHOD1 GGT7 GPR42 GPX8 HSD17B11 LCN2 LHFPL5 MMGT1 REEP4 REL SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A	23 interacting genes: ADIPOQ ATP6V0C BCL2L2 BIK BNIP2 C4orf3 CSGALNACT2 FAM209A FFAR2 FXYD6 GET1 GPR25 LNPEP PLP1 RUSF1 SELENOK SLC66A2 SPG21 SSMEM1 TMEM14B TMEM234 TMEM60 TTPA
Entrez ID		4012	55508
HPRD ID		01041	15375
Ensembl ID		ENSG00000113441	ENSG00000175782
Uniprot IDs		Q9UIQ6	A0A024RB82 Q7Z769
PDB IDs		4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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