LNPEP and SLC39A9

Data Source:
BioGRID (two hybrid)

		LNPEP	SLC39A9
Description		leucyl and cystinyl aminopeptidase	solute carrier family 39 member 9
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Lysosomal Membrane Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Early Endosome Lumen	Integral Component Of Membrane
	Molecular Function	Aminopeptidase Activity Protein Binding Metallopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity	Protein Binding Metal Ion Transmembrane Transporter Activity
	Biological Process	Protein Polyubiquitination Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Proteolysis Signal Transduction Cell-cell Signaling Female Pregnancy Regulation Of Blood Pressure Peptide Catabolic Process Negative Regulation Of Cold-induced Thermogenesis	Zinc Ion Transport Transmembrane Transport
Pathways		Endosomal/Vacuolar pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Acute anterior uveitis (with or without ankylosing spondylitis) ( 25200001) Ankylosing spondylitis ( 23749187) Birdshot chorioretinopathy ( 24957906) Blood protein levels ( 28240269) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908 23128233) Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761) Lymphocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494)	Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		33 interacting genes: AGT AQP6 ASGR2 CGRRF1 CTAG1A CTAG1B FAM210B FATE1 FCER1G FHOD1 GGT7 GPR42 GPX8 HSD17B11 LCN2 LHFPL5 MMGT1 REEP4 REL SLC2A4 SLC35E3 SLC39A9 SMAD9 SSMEM1 STOM TAS2R19 TCF4 TLCD4 TMEM35A TNKS TNKS2 UBQLN1 UNC93A	40 interacting genes: ANKRD46 APH1A AQP6 BNIP2 CBARP CD79A CERS3 CPLX4 CRB3 CREB3L1 CREB3L3 CYB5B ELOVL5 EVI2B FCER1G FFAR2 GJA8 GPR101 HERPUD2 HTR2C LNPEP MANBAL MFSD14B MFSD5 MGST3 NEU1 RTP2 SERINC2 SLC10A6 SLC16A2 SLC39A2 SLC66A1 SLC7A1 SSMEM1 TM4SF18 TMEM140 TMEM237 TMEM86B TRHR VMP1
Entrez ID		4012	55334
HPRD ID		01041	15387
Ensembl ID		ENSG00000113441	ENSG00000029364
Uniprot IDs		Q9UIQ6	B4DDK0 C4N9M8 M0QX28 Q9NUM3
PDB IDs		4P8Q 4PJ6 4Z7I 5C97 5JHQ 5MJ6
Enriched GO Terms of Interacting Partners?
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