LMAN1 and BCAP31

Data Source:
BioGRID (fluorescent resonance energy transfer, imaging technique)

		LMAN1	BCAP31
Description		lectin, mannose binding 1	B cell receptor associated protein 31
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol ER To Golgi Transport Vesicle Membrane Membrane Integral Component Of Membrane Sarcomere COPII-coated ER To Golgi Transport Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Collagen-containing Extracellular Matrix Extracellular Exosome	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Perinuclear Endoplasmic Reticulum
	Molecular Function	Protein Binding Mannose Binding Metal Ion Binding Unfolded Protein Binding	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Blood Coagulation Positive Regulation Of Organelle Organization Protein N-linked Glycosylation Via Asparagine Protein Exit From Endoplasmic Reticulum Early Endosome To Golgi Transport COPII Vesicle Coating Negative Regulation Of Protein Targeting To Mitochondrion	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Targeting To Mitochondrion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Viral Process Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Endoplasmic Reticulum Stress Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER Transport to the Golgi and subsequent modification	Apoptotic cleavage of cellular proteins Apoptotic execution phase Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs		Antihemophilic factor, human recombinant Lonoctocog alfa Moroctocog alfa
Diseases		Combined deficiency of factors V and VIII (F5F8D)
GWAS		Cardiac troponin-I levels ( 31014085) Chronotype ( 27494321) Morning vs. evening chronotype ( 27494321)
Interacting Genes		4 interacting genes: APP BCAP31 F8 MCFD2	30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ
Entrez ID		3998	10134
HPRD ID		03338	02319
Ensembl ID		ENSG00000074695	ENSG00000185825
Uniprot IDs		A0A024R2A7 P49257	P51572
PDB IDs		3A4U 3LCP 3WHT 3WHU 3WNX 4GKX 4GKY 4YGB 4YGC 4YGD 4YGE	4JZL 4JZP
Enriched GO Terms of Interacting Partners?
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