BCAP31 and KLK10

Data Source:
BioGRID (two hybrid)

		BCAP31	KLK10
Description		B cell receptor associated protein 31	kallikrein related peptidase 10
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GO Annotations	Cellular Component	Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Integral Component Of Plasma Membrane Membrane Clathrin-coated Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitochondria-associated Endoplasmic Reticulum Membrane Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane Perinuclear Endoplasmic Reticulum	Extracellular Region Secretory Granule
	Molecular Function	Protein Binding MHC Class I Protein Binding Protein-containing Complex Binding	Serine-type Endopeptidase Activity Serine-type Peptidase Activity
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Protein Targeting To Mitochondrion Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Apoptotic Process Positive Regulation Of Cytosolic Calcium Ion Concentration Spermatogenesis Viral Process Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Response To Endoplasmic Reticulum Stress Calcium-mediated Signaling Using Intracellular Calcium Source Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Mitochondrial Calcium Ion Concentration Protein Localization To Endoplasmic Reticulum Exit Site Positive Regulation Of ER-associated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Retrograde Protein Transport, ER To Cytosol Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Proteolysis Cell Cycle
Pathways		Apoptotic cleavage of cellular proteins Apoptotic execution phase Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		30 interacting genes: ACTG1 APP AQP2 BCAP29 BCL2 BCL2L1 CANX CASP1 CASP3 CASP8 CDC42 DRD2 FIS1 GPRIN2 HACD2 HLA-A IGHD KLK10 LMAN1 MSN MYH10 PLP2 SERPINF2 TIMMDC1 TMEM31 VAMP1 VAMP2 VAMP3 VKORC1 YWHAQ	2 interacting genes: BCAP31 LRIF1
Entrez ID		10134	5655
HPRD ID		02319	04054
Ensembl ID		ENSG00000185825	ENSG00000129451
Uniprot IDs		P51572	O43240
PDB IDs		4JZL 4JZP	5LPE 5LPF
Enriched GO Terms of Interacting Partners?
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