LAMP2 and AP4M1

Data Source:
HPRD (in vitro)

		LAMP2	AP4M1
Description		lysosomal associated membrane protein 2	adaptor related protein complex 4 subunit mu 1
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GO Annotations	Cellular Component	Extracellular Space Lysosome Lysosomal Membrane Late Endosome Plasma Membrane Membrane Phagocytic Vesicle Membrane Platelet Dense Granule Membrane Late Endosome Membrane Azurophil Granule Membrane Lysosomal Lumen Autolysosome Membrane Raft Extracellular Exosome Integral Component Of Autophagosome Membrane Membrane Microdomain Ficolin-1-rich Granule Membrane Lysosomal Matrix	Early Endosome Trans-Golgi Network Cytosol AP-4 Adaptor Complex Clathrin Adaptor Complex Cytoplasmic Vesicle Endosome Lumen Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding Protein Domain Specific Binding	Protein Binding Protein Domain Specific Binding
	Biological Process	Platelet Degranulation Protein Targeting Cellular Response To Starvation Protein Import Regulation Of Protein Stability Neutrophil Degranulation Muscle Cell Cellular Homeostasis Protein Stabilization Chaperone-mediated Autophagy Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy Establishment Of Protein Localization To Organelle Autophagosome Maturation Lysosomal Protein Catabolic Process	Protein Targeting Protein Targeting To Lysosome Intracellular Protein Transport Golgi To Endosome Transport Protein Localization Vesicle-mediated Transport Golgi To Lysosome Transport Protein Localization To Basolateral Plasma Membrane
Pathways		Platelet degranulation Neutrophil degranulation Chaperone Mediated Autophagy	Lysosome Vesicle Biogenesis
Drugs
Diseases		Danon disease; X-linked vacuolar cardiomyopathy and myopathy	Cerebral palsy
GWAS			Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: AP4M1 APLNR CTSA PIAS4 UCHL1	14 interacting genes: AP4B1 ARF1 CACNG3 CD63 CHTF8 DDX52 FNTA GRID2 GRIN2A GRIN2B LAMP2 TGOLN2 USP47 ZBTB22
Entrez ID		3920	9179
HPRD ID		02396	03803
Ensembl ID		ENSG00000005893	ENSG00000221838
Uniprot IDs		P13473	C9JC87 O00189
PDB IDs		2MOF 2MOM	3L81 4MDR
Enriched GO Terms of Interacting Partners?
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