LAD1 and COL17A1

Data Source:
HPRD (in vitro)

		LAD1	COL17A1
Description		ladinin 1	collagen type XVII alpha 1 chain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Basement Membrane Actin Cytoskeleton Extracellular Exosome	Extracellular Region Collagen Trimer Basement Membrane Extracellular Space Endoplasmic Reticulum Lumen Plasma Membrane Integral Component Of Plasma Membrane Cell-cell Junction Hemidesmosome Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Structural Molecule Activity Cadherin Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process		Cell-matrix Adhesion Epidermis Development Extracellular Matrix Organization Hemidesmosome Assembly Regulation Of Immune Response
Pathways			Collagen degradation Collagen biosynthesis and modifying enzymes Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Assembly of collagen fibrils and other multimeric structures Type I hemidesmosome assembly Collagen chain trimerization
Drugs
Diseases			Epidermolysis bullosa, junctional, including: Epidermolysis bullosa, junctional, Herlitz type (JEB-H); Epidermolysis bullosa, junctional, non-Herlitz type (JEB-nH); Epidermolysis bullosa, junctional, with pyloric atresia (JEB-PA)
GWAS		Height ( 28552196) Triglyceride levels ( 30108155)	Cardiac hypertrophy ( 21348951)
Interacting Genes		2 interacting genes: APP COL17A1	18 interacting genes: ACTN1 ACTN4 CLSTN1 CSTF2T CTNND1 DSP DST ITGA6 ITGB4 KRT18 LAD1 PLEC PLOD3 PNKP PPIL1 PPL UBQLN2 WHRN
Entrez ID		3898	1308
HPRD ID		03815	00223
Ensembl ID		ENSG00000159166	ENSG00000065618
Uniprot IDs		O00515	Q9UMD9
PDB IDs
Enriched GO Terms of Interacting Partners?
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