SLC9A4 and CHP1

Data Source:
HPRD (in vivo, in vitro)

		SLC9A4	CHP1
Description		solute carrier family 9 member A4	calcineurin like EF-hand protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Vacuolar Membrane Plasma Membrane Integral Component Of Membrane Basolateral Plasma Membrane Apical Plasma Membrane	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Exosome
	Molecular Function	Sodium:proton Antiporter Activity Potassium:proton Antiporter Activity	Protein Kinase Inhibitor Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding
	Biological Process	Gastric Acid Secretion Epithelial Cell Development Ion Transport Response To Salt Stress Regulation Of Intracellular PH Potassium Ion Homeostasis Potassium Ion Transmembrane Transport Anion Transmembrane Transport Sodium Ion Import Across Plasma Membrane Proton Transmembrane Transport	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Vesicle Targeting Vesicle Fusion Small GTPase Mediated Signal Transduction Negative Regulation Of Phosphatase Activity Membrane Docking Hyaluronan Catabolic Process Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Protein Stabilization Positive Regulation Of Protein Transport Protein Complex Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Positive Regulation Of Phospholipid Biosynthetic Process Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death
Pathways		Sodium/Proton exchangers	Hyaluronan uptake and degradation
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Basophil count ( 32888494) Bisphosphonate-associated atypical femoral fracture ( 31006051) Blood protein levels ( 28240269) Celiac disease ( 25920553 30572963 18311140) Crohn's disease ( 28067908) Delirium ( 29631748) Estimated glomerular filtration rate ( 31152163) Inflammatory bowel disease ( 28067908) Lymphocyte counts ( 27863252) Mean corpuscular hemoglobin concentration ( 32888494) Night sleep phenotypes ( 27126917) Serum protein levels (sST2) ( 23999434) White blood cell types ( 21738478)	Allergic disease (asthma, hay fever or eczema) ( 29785011) Essential hypertension (time to event) ( 32589924) Estimated glomerular filtration rate ( 31015462) Ulcerative colitis ( 28067908) White blood cell count ( 32888494)
Interacting Genes		2 interacting genes: CHP1 CHP2	10 interacting genes: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B UBC
Entrez ID		389015	11261
HPRD ID		15973	06101
Ensembl ID		ENSG00000180251	ENSG00000187446
Uniprot IDs		Q6AI14	A0A024R9M9 H0YKE7 Q99653
PDB IDs			2E30
Enriched GO Terms of Interacting Partners?
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